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Proteins/UNIPROT:Q9NYS0
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB..
Function from UniProtKB (Q9NYS0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
82 statements
82 statements · 3 reference databases · Subject: NKIRAS1 · Sources: gene ontology, Hetionet, Reactome
4 names
Resolves to: NKIRAS1