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Proteins/UNIPROT:Q96AX9
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors..
Function from UniProtKB (Q96AX9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
67 statements
67 statements · 4 reference databases · Subject: MIB2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
1 reaction
9 names
Resolves to: MIB2
Reaction pageLeft to rightBalance undeterminableEC 2.3.2.23, 2.3.2.27, 6.2.1.45cytosol
Human-GEM MAR09491CC BY 4.0Reference data