Compound
17alpha-estradiol
No description recorded for this entry yet. Everything this graph holds about 17alpha-estradiol is below.
Structure
- Class
- Organic compound
- Formula
- C18H24O2
- Mass
- 272.388 g/mol
- Charge
- 0
- InChIKey
- VOXZDWNPVJITMN-SFFUCWETSA-N
- SMILES
- [H][C@@]12CCc3cc(O)ccc3[C@@]1([H])CC[C@]1(C)[C@H](O)CC[C@@]21[H]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says 17alpha-estradiol moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
11 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
11 entities
11 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hops11 assembled from the scaffold
- UGT1A1ProteinUNIPROT:P22309metabolized byInferred only25 paths25 endpoints
- UGT2B17ProteinUNIPROT:O75795metabolized byInferred only18 paths9 endpoints
- UGT2A1ProteinUNIPROT:P0DTE4metabolized byInferred only16 paths8 endpoints
- UGT2B7ProteinUNIPROT:P16662metabolized byInferred only16 paths16 endpoints
- UGT1A3ProteinUNIPROT:P35503metabolized byInferred only15 paths15 endpoints
- UGT1A10ProteinUNIPROT:Q9HAW8metabolized byInferred only14 paths14 endpoints
- UGT1A7ProteinUNIPROT:Q9HAW7metabolized byInferred only12 paths12 endpoints
- UGT2B4ProteinUNIPROT:P06133metabolized byInferred only11 paths11 endpoints
- UGT1A8ProteinUNIPROT:Q9HAW9metabolized byInferred only11 paths11 endpoints
- UGT2B15ProteinUNIPROT:P54855metabolized byInferred only10 paths10 endpoints
- UGT2A2ProteinUNIPROT:P0DTE5metabolized byInferred only9 paths9 endpoints
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from 17alpha-estradiol: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Statements
16 statements
16 statements in 1 reference database name 17alpha-estradiol — Rhea. Press a relation to see only its rows; every count is the rows behind it.
- 17alpha-estradiol is converted to estroneCompoundRhea RHEA:16705Inferred only
- estrone is converted to 17alpha-estradiolCompoundRhea RHEA:16705Inferred only
- 17alpha-estradiol is metabolised by UGT1A1ProteinRhea RHEA:52868Inferred only
- 17alpha-estradiol is metabolised by UGT1A10ProteinRhea RHEA:52868Inferred only
- 17alpha-estradiol is metabolised by UGT1A3ProteinRhea RHEA:52868Inferred only
- 17alpha-estradiol is metabolised by UGT1A7ProteinRhea RHEA:52868Inferred only
- 17alpha-estradiol is metabolised by UGT1A8ProteinRhea RHEA:52868Inferred only
- 17alpha-estradiol is metabolised by UGT2A1ProteinRhea RHEA:52868Inferred only
- 17alpha-estradiol is metabolised by UGT2A1ProteinRhea RHEA:52872Inferred only
- 17alpha-estradiol is metabolised by UGT2A2ProteinRhea RHEA:52868Inferred only
- 17alpha-estradiol is metabolised by UGT2B15ProteinRhea RHEA:52868Inferred only
- 17alpha-estradiol is metabolised by UGT2B17ProteinRhea RHEA:52868Inferred only
Show the remaining 4
- 17alpha-estradiol is metabolised by UGT2B17ProteinRhea RHEA:52872Inferred only
- 17alpha-estradiol is metabolised by UGT2B4ProteinRhea RHEA:52872Inferred only
- 17alpha-estradiol is metabolised by UGT2B7ProteinRhea RHEA:52872Inferred only
- 17alpha-estradiol is a substrate of DHRS1ProteinRhea RHEA:16705Inferred only
Other names
25 names
Every name this graph resolves to 17alpha-estradiol. Searching any of them lands here.
- Also called
- (17alpha)-estra-1,3,5(10)-triene-3,17-diol(17α)-estra-1,3,5(10)-triene-3,17-diol1,3,5-estratriene-3,17alpha-diol1,3,5-estratriene-3,17α-diol13beta-methyl-1,3,5(10)-gonatriene-3,17alpha-diol13β-methyl-1,3,5(10)-gonatriene-3,17α-diol17-epiestradiol17alpha-oestradiol17α-oestradiol3,17alpha-dihydroxyestra-1,3,5(10)-triene3,17alpha-dihydroxyoestra-1,3,5(10)-triene3,17α-dihydroxyestra-1,3,5(10)-triene3,17α-dihydroxyoestra-1,3,5(10)-trienealfatradiolalpha-estradiolepiestradiolepiestrolestra-1,3,5(10)trien-3,17alpha-diolEstradiol-17alphaoestra-1,3,5(10)-triene-3,17alpha-dioloestra-1,3,5(10)-triene-3,17α-diolST 18:3;O2α-estradiol
- Systematic name
- estra-1,3,5(10)-triene-3,17alpha-diolestra-1,3,5(10)-triene-3,17α-diol