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an aromatic L-alpha-amino acid

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

9 compounds within 3 steps: 1 in 1, 1 in 2, 7 in 3

Does it reach a compound?

One step

an N-acyl-aromatic L-alpha-amino acidReach from here →
1. an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
Catalysed by PM20D1, ACY3

Two steps

a carboxylateReach from here →
1. an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
2. an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
Catalysed by PM20D1, ACY3

Three steps

an aldehydeReach from here →
Catalysed by PM20D1, ACY3, AOX1
orotateReach from here →
Catalysed by PM20D1

inner side of the membrane, outer side of the membrane

One of 2 routes

a carboxylic esterReach from here →

an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
a carboxylic ester + H2O = an alcohol + a carboxylate + H(+)

Catalysed by PM20D1, ACY3, CES2, CES1 and 3 more

an acylcholineReach from here →

an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
an acylcholine + H2O = a carboxylate + choline + H(+)

Catalysed by PM20D1, ACY3, BCHE

a thioesterReach from here →

an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
a thioester + H2O = a thiol + a carboxylate + H(+)

Catalysed by PM20D1, ACY3, PNKD

a 3-acylpyruvateReach from here →

an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)

Catalysed by PM20D1, ACY3, FAHD1

an N-acyl-L-amino acidReach from here →

an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate
an N-acyl-L-amino acid + H2O = an L-alpha-amino acid + a carboxylate

Catalysed by PM20D1, ACY3, ACY1