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indole-3-acetaldehyde

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

16 compounds within 3 steps: 1 in 1, 2 in 2, 13 in 3

Does it reach a compound?

One step

(indol-3-yl)acetateReach from here →
1. Indole-3-acetaldehyde:NAD+ oxidoreductase
Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 1 morecytosolOne of 2 routes

Two steps

a dicarboxylateReach from here →
1. Indole-3-acetaldehyde:NAD+ oxidoreductase
2. (indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
methyl (indol-3-yl)acetateReach from here →
1. Indole-3-acetaldehyde:NAD+ oxidoreductase
2. S-adenosyl-L-methionine:(indol-3-yl)acetate O-methyltransferase
Catalysed by ALDH2, ALDH1B1, ALDH9A1 and 3 more

Three steps

indoxyl sulfateReach from here →
Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
sulfateReach from here →

cytosol

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 5 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

urateReach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
urate(out) + a dicarboxylate(in) = urate(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

3-carboxy-4-methyl-5-propyl-2-furanpropanoateReach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
3-carboxy-4-methyl-5-propyl-2-furanpropanoate(out) + a dicarboxylate(in) = 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

L-sepiapterinReach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
L-sepiapterin(out) + a dicarboxylate(in) = L-sepiapterin(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

L-erythro-7,8-dihydrobiopterinReach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
L-erythro-7,8-dihydrobiopterin(out) + a dicarboxylate(in) = L-erythro-7,8-dihydrobiopterin(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

prostaglandin F2alphaReach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
prostaglandin F2alpha(out) + a dicarboxylate(in) = prostaglandin F2alpha(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

3',5'-cyclic GMPReach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
3',5'-cyclic GMP(out) + a dicarboxylate(in) = 3',5'-cyclic GMP(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

3',5'-cyclic AMPReach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
3',5'-cyclic AMP(out) + a dicarboxylate(in) = 3',5'-cyclic AMP(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

kynurenateReach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
kynurenate(out) + a dicarboxylate(in) = kynurenate(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

(6R)-L-erythro-5,6,7,8-tetrahydrobiopterinReach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in) = (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

prostaglandin E2Reach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
prostaglandin E2(out) + a dicarboxylate(in) = prostaglandin E2(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

N-benzoylglycineReach from here →

Indole-3-acetaldehyde:NAD+ oxidoreductase
(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)
N-benzoylglycine(out) + a dicarboxylate(in) = N-benzoylglycine(in) + a dicarboxylate(out)

Catalysed by ALDH2, ALDH1B1, ALDH9A1, ALDH7A1 and 3 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes