Compound
sodium benzoate
No description recorded for this entry yet. Everything this graph holds about sodium benzoate is below.
Structure
- Formula
- C7H5O2.Na
- Mass
- 144.105 g/mol
- Charge
- 0
- InChIKey
- WXMKPNITSTVMEF-UHFFFAOYSA-M
- SMILES
- O=C([O-])c1ccccc1.[Na+]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from sodium benzoate: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Regulatory determinations
Published numbers and scores, transcribed from the body that issued them. A determination is not a finding and is not graded; it is the number, who set it, and the document it came from.
LiverTox likelihood score ELiverTox
LiverTox Likelihood Score E — despite extensive use, no evidence that the agent has caused liver injury. Chapter: "Phenylbutyrate, Sodium Benz.". Source: LiverTox Master List (NBK571102).
The document·Public Domain (NLM/NIH)·Transcribed, not graded
Statements
1 statement
1 statement in 1 reference database name sodium benzoate — ChEBI. Press a relation to see only its rows; every count is the rows behind it.
- sodium benzoate is converted to benzoic acidCompoundChEBI CHEBI:113455Inferred only
Registered, and not reported
The findings above are what the literature reported about sodium benzoate. This is what it registered and did not: trials on ClinicalTrials.gov that list sodium benzoate as an intervention, reached completed, terminated or suspended, and posted no results. It says nothing about what those trials found — that is the point.
Trials without posted results
53 trials
53 registered trials without posted results. 50 passed an actual primary completion date more than a year ago, which is the reporting window FDAAA 801 sets.
50 past the window3 within it, or no actual date
- NCT05006781suspended— The trial was suspended due to the budget issueexpected 2028-12a university or hospital
- NCT06374641completed2025-06-06a university or hospitalpast the reporting window
- NCT04649229completed2025-05-22a university or hospitalpast the reporting window
- NCT03620773completed2024-09-25a university or hospitalpast the reporting window
- NCT03469011terminated— Lack of Accrual2024-07-31a university or hospitalpast the reporting window
- NCT05923723completed2024-06-18a university or hospitalpast the reporting window
- NCT07240051completed2024-06-10a university or hospitalpast the reporting window
- NCT05129722terminated— Difficulties in recruitment at both sites.2024-05-01a university or hospitalpast the reporting window
- NCT06148662completed2024-01-25a university or hospitalpast the reporting window
- NCT06122467completed2023-12-31industrypast the reporting window
- NCT06969495completed2023-11-30a university or hospitalpast the reporting window
- NCT05726097completed2023-10-31a university or hospitalpast the reporting window
Show the remaining 41
- NCT01908192terminated2023-10-26industrypast the reporting window
- NCT06358911completed2023-08-05a university or hospitalpast the reporting window
- NCT03573921terminated— Poor recruitment to date.2022-12-19a university or hospitalpast the reporting window
- NCT02537314completed2022-12-08a university or hospitalpast the reporting window
- NCT04407481completed2022-10-13a university or hospitalpast the reporting window
- NCT04969120completed2022-07-01a university or hospitalpast the reporting window
- NCT04074668completed2022-05-15a university or hospitalpast the reporting window
- NCT04910906completed2022-02-09industrypast the reporting window
- NCT04494529completed2021-08-31a university or hospitalpast the reporting window
- NCT03652974completed2021-08-30a university or hospitalpast the reporting window
- NCT04902105completed2021-07-06industrypast the reporting window
- NCT05475314completed2021-04-30industrypast the reporting window
- NCT03510741completed2020-12-30a university or hospitalpast the reporting window
- NCT04492839completed2020-10-01a university or hospitalpast the reporting window
- NCT01456208terminated— Funding stopped2020-06a university or hospitalpast the reporting window
- NCT04872946completed2020-05-07industrypast the reporting window
- NCT02546583completed2020-01-23a university or hospitalpast the reporting window
- NCT01511042terminated2020-01a university or hospitalpast the reporting window
- NCT03380754completed2019-08-01a university or hospitalpast the reporting window
- NCT04884464completed2019-06-30a university or hospitalpast the reporting window
- NCT04022941completed2018-12-31a university or hospitalpast the reporting window
- NCT03838068completed2018-12-30a university or hospitalpast the reporting window
- NCT02627950completed2018-10a university or hospitalpast the reporting window
- NCT05139966completed2018-09-12a university or hospitalpast the reporting window
- NCT03819179completed2018-02-06a university or hospitalpast the reporting window
- NCT03383315completed2017-09-30a university or hospitalpast the reporting window
- NCT01937234completed2016-07a university or hospitalpast the reporting window
- NCT02196662completed2015-04industrypast the reporting window
- NCT02558192completed2014-10a university or hospitalpast the reporting window
- NCT01349205terminated— The study medication was no longer available in the market2014-06a university or hospitalpast the reporting window
- NCT01596166completed2014-04a university or hospitalpast the reporting window
- NCT01179945completed2011-08a university or hospitalpast the reporting window
- NCT01191645completed2010-11a university or hospitalpast the reporting window
- NCT00808977completed2010-06industrypast the reporting window
- NCT01858090completed2009-10a university or hospitalpast the reporting window
- NCT01225198completed2009-02a university or hospitalpast the reporting window
- NCT00091078terminated2006-07NIHpast the reporting window
- NCT00049192completed2005-11NIHpast the reporting window
- NCT00004245completed2004-09a university or hospitalpast the reporting window
- NCT00004767completedno completion dateNIH
- NCT00977600completedno completion dateindustry
Papers screened
29 papers
29 papers screened for sodium benzoate. 0 produced a finding, 4 were read and discarded, 25 have not been read yet. Each group opens to the papers in it.
The whole record lists every paper, the query that retrieved it and the date it was decided.
Discarded: an endpoint this vocabulary does not hold3 papers
- PMID:34890931no claim extracted — no_outcome_node — measured: positive symptoms of schizophrenia, pooled as mean difference (PANSS positive subscale presumed; not named in abstract) | Positive symptoms of schizophrenia (PANSS positive subscale), pooled mean difference for add-on sodium benzoate vs placebo (MD -1.87, 95% CI -3.25 to -0.48; p=0.008); and extrapyramidal symptoms, pooled mean difference, significantly higher on sodium benzoate (MD 0.39, 95% CI 0.19-0.60; p=0.0002) — neither has a matching outcome node2026-09-04
- PMID:39450675no claim extracted — no_outcome_node — measured: Alzheimer's disease assessment scale-cognitive subscale (ADAS-cog), pooled as mean difference from baseline to endpoint | ADAS-cog score (Alzheimer's Disease Assessment Scale-cognitive subscale), pooled mean difference, sodium benzoate vs placebo in mild Alzheimer's disease RCTs (MD -2.13, 95% CI -3.35 to -0.90; P=0.0007)2026-09-04
- PMID:41863585no claim extracted — no_outcome_node — measured: cognitive improvement, pooled effect size across five RCTs (no specific cognitive test instrument named in the abstract) | Cognitive improvement, overall effect size pooled across unspecified/multiple cognitive tests, in patients with dementia or mild cognitive impairment receiving sodium benzoate vs placebo, gender-stratified meta-analysis2026-09-04
Discarded: no extractable result1 paper
- PMID:39975997claims extracted but refused by the deterministic validators2026-09-04
Not read yet25 papers
- PMID:117661312026-09-01
- PMID:155901202026-09-01
- PMID:276117152026-09-01
- PMID:297682882026-09-01
- PMID:298428812026-09-01
- PMID:329894612026-09-01
- PMID:351877462026-09-01
- PMID:354061092026-09-01
- PMID:354302672026-09-01
- PMID:355250872026-09-01
- PMID:367284032026-09-01
- PMID:369271852026-09-01
and 13 more.
Other names
2 names
Every name this graph resolves to sodium benzoate. Searching any of them lands here.
- Also called
- Benzoic acid, sodium saltE211