sodium benzoate/Finding
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Inhibits RUNX2
SpeculativeGrade F, Speculative. Mechanistic inference, or no evidence found.Finding“The rescue studies suggested that NaB inhibited RUNX2 expression and osteoblast differentiation through the p38/MAPK signaling pathway.”
Quoted verbatim from Sodium Benzoate Inhibits Osteoblast Differentiation and Accelerates Bone Loss by Regulating the FGF2/p38/RUNX2 Pathway.. - Study
- in vitro · not in humans
- Population
- bone marrow mesenchymal stem cells and MC3T3-E1 osteoblast-lineage cells
Sodium Benzoate Inhibits Osteoblast Differentiation and Accelerates Bone Loss by Regulating the FGF2/p38/RUNX2 Pathway.2025PMID:40404584Permalink
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To cite this finding: https://catalystproject.ai/e/01M37X3EGWVVZ1735108SXRX30