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sodium benzoateFinding

Sodium benzoate inhibits RUNX2

lowersInsufficient evidenceFinding

01 · The sentence it was drawn from

“The rescue studies suggested that NaB inhibited RUNX2 expression and osteoblast differentiation through the p38/MAPK signaling pathway.”
Quoted verbatim from Sodium Benzoate Inhibits Osteoblast Differentiation and Accelerates Bone Loss by Regulating the FGF2/p38/RUNX2 Pathway. · PMID 40404584 · 2025
RUNX2 · this finding in ember among the 1 finding on it, in bands by direction at evidence strength

Findingsodium benzoate

RUNX2

inhibits

Effect as reported

not reported

Who
bone marrow mesenchymal stem cells and MC3T3-E1 osteoblast-lineage cells
Dose studied
not reported

Insufficient evidencePMID 40404584 · 2025

02 · The finding

inhibits

Insufficient

Mechanistic inference, no evidence found, or evidence weakened below very limited

Endpoint

RUNX2

Study
in vitro · not in humans
Participants
not reported
Duration
not reported
Kind
Finding Reported directly by a cited source.

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limited
  • insufficientthis finding

03 · The paper

Journal of agricultural and food chemistry · 2025
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M37X3EGWVVZ1735108SXRX30