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Papers/PMID:40404584

Sodium Benzoate Inhibits Osteoblast Differentiation and Accelerates Bone Loss by Regulating the FGF2/p38/RUNX2 Pathway.

Journal of agricultural and food chemistry2025The record

1 finding · 1 compound · 1 endpoint

sodium benzoate

What it reported

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What moved

1 finding

sodium benzoate — inhibits RUNX2
SpeculativeGrade F, Speculative. Mechanistic inference, or no evidence found.Finding
“The rescue studies suggested that NaB inhibited RUNX2 expression and osteoblast differentiation through the p38/MAPK signaling pathway.”
Quoted verbatim from Sodium Benzoate Inhibits Osteoblast Differentiation and Accelerates Bone Loss by Regulating the FGF2/p38/RUNX2 Pathway..
Study

in vitro · not in humans
Population

bone marrow mesenchymal stem cells and MC3T3-E1 osteoblast-lineage cells
Sodium Benzoate Inhibits Osteoblast Differentiation and Accelerates Bone Loss by Regulating the FGF2/p38/RUNX2 Pathway.2025PMID:40404584Permalink