PapersPMID:38150747
Sodium benzoate induces pancreatic inflammation and β cell apoptosis partially via benzoylation.
- 01 · finding
- 1
- 02 · compound
- 1
- 03 · endpoint
- 1
- 04 · null
- 0
What moved
1 findingHow to read these marks →sodium benzoate — is converted to benzoyl-CoA
insufficientFinding
“Furthermore, NAB concentration-dependently increases benzoyl-CoA and Kbz levels.”
Quoted verbatim from Sodium benzoate induces pancreatic inflammation and β cell apoptosis partially via benzoylation. - Study
- in vitro · not in humans
- Population
- β-TC-6 pancreatic β cells treated with NAB
Study record
- Read under
- sodium benzoate
- Design
- animal study, in vivo
- Species
- mixed
- Population
- C57BL/6J mice (NAB in drinking water, 1 g/kg) and beta-TC-6 pancreatic beta cells (6 mM NAB or 100 uM benzoyl-CoA +/- inhibitors)
- Participants
- not recorded
- Comparator
- an active treatment / no treatment / placebo
- Duration
- not recorded
- Endpoints measured
- 6
- Record
- extracted
- Readings recorded
- 3