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Reference

Evidence

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Reactions
Reach

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Pathways
Processes
Anatomy
Cell types
Organisms
Materials
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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:Q9UKI9

POU2F3

Protein·UNIPROT:Q9UKI91 finding

Open in the graph

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues..

Function from UniProtKB (Q9UKI9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

Findings that name it directly

sodium benzoateinhibitsInsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

4 statements

4 statements · 2 reference databases · Subject: POU2F3 · Sources: gene ontology, Hetionet

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POU2F3 covaries with DEFB1ProteinHetionet hetionet:covaries:1672-25833Inferred only
POU2F3 covaries with SPACA3ProteinHetionet hetionet:covaries:124912-25833Inferred only
POU2F3 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q9UKI9|GO:0045944Inferred only
POU2F3 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q9UKI9|GO:0006357Inferred only

Sources cited

1 paper

Subject: POU2F3
Findings: 1
Papers: 1

Sodium Benzoate Induces Fat Accumulation and Reduces Lifespan via the SKN-1/Nrf2 Signaling Pathway: Evidence from the Caenorhabditis elegans Model.record2024PMID:395195841 finding

Other names

10 names

Resolves to: POU2F3

Also called: Oct-11Octamer-binding protein 11Octamer-binding transcription factor 11OTF-11OTF11PLA-1PLA1Skn-1Transcription factor PLA-1Transcription factor Skn-1

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