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Proteins/UNIPROT:P41225
Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity)..
Function from UniProtKB (P41225), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
9 rows
95 statements
95 statements · 3 reference databases · Subject: SOX3 · Sources: gene ontology, Hetionet, Reactome
2 names
Resolves to: SOX3