Loading the page.
Proteins/UNIPROT:Q8NBM8
Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine. Does not metabolize shorter prenyl chain compounds (Probable). Required in the mevalonate pathway to regulate prenylation and enhances the bactericidal activity of neutrophils (By similarity). Promotes the assembly of the postsynaptic ion channel ASIC1a (By similarity)..
Function from UniProtKB (Q8NBM8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
32 statements
32 statements · 4 reference databases · Subject: PCYOX1L · Sources: Hetionet, Reactome, Rhea, UniProt
2 reactions
S-(2E,6E)-farnesyl-L-cysteine+dioxygen+water(2E,6E)-farnesal+L-cysteine+hydrogen peroxide
Catalysed by PCYOX1L or PCYOX1
Reaction pageLeft to rightBalanced
Rhea RHEA:30231CC BY 4.0Reference data
[(2E,6E,10E)-geranylgeranyl]-L-cysteine+dioxygen+water(2E,6E,10E)-geranylgeranial+
1 name
Resolves to: PCYOX1L
Reaction pageLeft to rightBalanced
Rhea RHEA:70407CC BY 4.0Reference data