Proteins/UNIPROT:Q9Y512

SAMM50

ProteinUNIPROT:Q9Y512

Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex..

Function from UniProtKB (Q9Y512), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

21 statements

21 statements · 3 reference databases · Subject: SAMM50 · Sources: Hetionet, Reactome, WikiPathways

Order

MEOX2 interacts with SAMM50ProteinHetionet hetionet:interacts:25813-4223Inferred only
UBC interacts with SAMM50ProteinHetionet hetionet:interacts:25813-7316Inferred only
SAMM50 participates in Cristae formationPathwayReactome R-HSA-8949613Inferred only
SAMM50 participates in Mitochondrial biogenesisPathwayReactome R-HSA-1592230Inferred only
SAMM50 participates in Mitochondrial protein importPathwayReactome R-HSA-1268020Inferred only
SAMM50 participates in MitophagyPathwayWikiPathways WP5636Inferred only
SAMM50 participates in Organelle biogenesis and maintenancePathwayReactome R-HSA-1852241Inferred only
SAMM50 participates in Protein localizationPathwayReactome R-HSA-9609507Inferred only
SAMM50 participates in RAC2 GTPase cyclePathwayReactome R-HSA-9013404Inferred only
SAMM50 participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
SAMM50 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
SAMM50 participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only

Show the remaining 9

SAMM50 participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only
AKR1C3 decreases the expression of SAMM50ProteinHetionet hetionet:regulates:8644-25813Inferred only
ERCC1 decreases the expression of SAMM50ProteinHetionet hetionet:regulates:2067-25813Inferred only
KSR2 decreases the expression of SAMM50ProteinHetionet hetionet:regulates:283455-25813Inferred only
MYCN increases the expression of SAMM50ProteinHetionet hetionet:regulates:4613-25813Inferred only
OAZ2 decreases the expression of SAMM50ProteinHetionet hetionet:regulates:4947-25813Inferred only
PRDM1 increases the expression of SAMM50ProteinHetionet hetionet:regulates:639-25813Inferred only
RIPK1 decreases the expression of SAMM50ProteinHetionet hetionet:regulates:8737-25813Inferred only
SOX3 increases the expression of SAMM50ProteinHetionet hetionet:regulates:6658-25813Inferred only

Other names

3 names

Resolves to: SAMM50

Also called: SAM50Transformation-related gene 3 proteinTRG-3

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