What it touches on the way
Mechanistic reach
16 entities
16 entities reached.
0 reported hops16 assembled from the scaffold
- melatoninCompoundCHEBI:16796converted toInferred only206 paths45 endpoints
- CYP1A2ProteinUNIPROT:P05177metabolized byInferred only39 paths39 endpoints
- CYP1A1ProteinUNIPROT:P04798metabolized byInferred only32 paths32 endpoints
- CYP1B1ProteinUNIPROT:Q16678metabolized byInferred only30 paths30 endpoints
- SULT1A3ProteinUNIPROT:P0DMM9metabolized byInferred only15 paths15 endpoints
- SULT1C2ProteinUNIPROT:O00338metabolized byInferred only12 paths12 endpoints
- CHST10ProteinUNIPROT:O43529substrate ofInferred only10 paths10 endpoints
- NDST1ProteinUNIPROT:P52848substrate ofInferred only8 paths8 endpoints
- HS2ST1ProteinUNIPROT:Q7LGA3substrate ofInferred only7 paths7 endpoints
- NDST4ProteinUNIPROT:Q9H3R1substrate ofInferred only7 paths7 endpoints
- CHST7ProteinUNIPROT:Q9NS84substrate ofInferred only7 paths7 endpoints
- SULT1B1ProteinUNIPROT:O43704metabolized byInferred only6 paths6 endpoints
Show the remaining 4
What the reference databases state
Statements
20 statements
20 statements · 1 reference database · Subject: CHEBI:308079 · Sources: Human-GEM
- melatonin is converted to CHEBI:308079CompoundHuman-GEM MAR08566Inferred only
- CHEBI:308079 is converted to melatoninCompoundHuman-GEM MAR04548Inferred only
- melatonin is converted to CHEBI:308079CompoundHuman-GEM MAR03119Inferred only
- melatonin is converted to CHEBI:308079CompoundHuman-GEM MAR04548Inferred only
- CHEBI:308079 is converted to melatoninCompoundHuman-GEM MAR03119Inferred only
- CHEBI:308079 is metabolised by CYP1A1ProteinHuman-GEM MAR04548Inferred only
- CHEBI:308079 is metabolised by CYP1A2ProteinHuman-GEM MAR04548Inferred only
- CHEBI:308079 is metabolised by CYP1B1ProteinHuman-GEM MAR04548Inferred only
- CHEBI:308079 is metabolised by SULT1A3ProteinHuman-GEM MAR04549Inferred only
- CHEBI:308079 is metabolised by SULT1B1ProteinHuman-GEM MAR04549Inferred only
- CHEBI:308079 is metabolised by SULT1C2ProteinHuman-GEM MAR04549Inferred only
- CHEBI:308079 is metabolised by SULT4A1ProteinHuman-GEM MAR04549Inferred only
Show the remaining 8
- CHEBI:308079 is a substrate of CHST10ProteinHuman-GEM MAR04549Inferred only
- CHEBI:308079 is a substrate of CHST5ProteinHuman-GEM MAR04549Inferred only
- CHEBI:308079 is a substrate of CHST7ProteinHuman-GEM MAR04549Inferred only
- CHEBI:308079 is a substrate of CHST9ProteinHuman-GEM MAR04549Inferred only
- CHEBI:308079 is a substrate of GAL3ST4ProteinHuman-GEM MAR04549Inferred only
- CHEBI:308079 is a substrate of HS2ST1ProteinHuman-GEM MAR04549Inferred only
- CHEBI:308079 is a substrate of NDST1ProteinHuman-GEM MAR04549Inferred only
- CHEBI:308079 is a substrate of NDST4ProteinHuman-GEM MAR04549Inferred only
Reactions
6 reactions
water+melatoninCHEBI:308079+2proton
Reaction pageReversibleUnbalancedEC 3.4.21.59cytosol
Human-GEM MAR03119CC BY 4.0Reference data
CHEBI:308079+protonwater+melatonin
Catalysed by CYP1B1 or CYP1A1 or CYP1A2
Reaction pageReversibleUnbalancedEC 1.14.14.1cytosol
Human-GEM MAR04548CC BY 4.0Reference data
MAM01162c+protonCHEBI:308079+sulfite
Catalysed by NDST1 or CHST10 or SULT4A1 or CHST5 or NDST4 or CHST7 or HS2ST1 or CHST9 or SULT1B1 or GAL3ST4 or SULT1C2 or SULT1A3
Reaction pageReversibleUnbalancedEC 2.8.2.-cytosol
Human-GEM MAR04549CC BY 4.0Reference data
proton+melatonin+NADPH(4-)+dioxygenCHEBI:308079+water+NADP(3-)
Catalysed by CYP1B1 or CYP1A1 or CYP1A2 or CYP2C19
Reaction pageLeft to rightBalancedEC 1.14.14.1cytosol
Human-GEM MAR08566CC BY 4.0Reference data
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR11921CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR11922CC BY 4.0Reference data