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Proteins/UNIPROT:Q9GZS9
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors. Acts on the non-reducing terminal GlcNAc of short carbohydrate substrates (in vitro). Preferentially add sulfate onto core 2- based O-glycan structures, but does not act on extended core 1 structures (in vitro). Involved in sulfation of endothelial mucins such as GLYCAM1. Has no activity toward keratan. Not involved in generating HEV-expressed ligands for SELL..
Function from UniProtKB (Q9GZS9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
8 statements
8 statements · 3 reference databases · Subject: CHST5 · Sources: Human-GEM, Reactome, WikiPathways
2 reactions
9 names
Resolves to: CHST5
MAM02312g+3'-phospho-5'-adenylyl sulfateproton+MAM02313g+adenosine 3',5'-bismonophosphate
Catalysed by CHST5 or CHST4 or CHST2 or CHST6
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.-Golgi apparatus
Human-GEM MAR07450CC BY 4.0Reference data