Proteins/UNIPROT:Q8TF61

FBXO41

ProteinUNIPROT:Q8TF61

Substrate-recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. Required in the developing brain for neuronal migration and long-term cerebellar integrity. Regulates postnatal hippocampal development, synaptic vesicle release probability at excitatory synapses and readily releasable pool size at inhibitory synapses. Upon accumulation at the centriole, promotes disassembly of primary cilia and negatively regulates Sonic hedgehog signaling..

Function from UniProtKB (Q8TF61), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

25 statements

25 statements · 2 reference databases · Subject: FBXO41 · Sources: Hetionet, Reactome

Order

FBXO41 covaries with B4GALT6ProteinHetionet hetionet:covaries:150726-9331Inferred only
FBXO41 covaries with DIO3ProteinHetionet hetionet:covaries:150726-1735Inferred only
FBXO41 covaries with DNAJB4ProteinHetionet hetionet:covaries:11080-150726Inferred only
FBXO41 covaries with GAL3ST3ProteinHetionet hetionet:covaries:150726-89792Inferred only
FBXO41 covaries with HES6ProteinHetionet hetionet:covaries:150726-55502Inferred only
FBXO41 covaries with HRH3ProteinHetionet hetionet:covaries:11255-150726Inferred only
FBXO41 covaries with HUNKProteinHetionet hetionet:covaries:150726-30811Inferred only
FBXO41 covaries with NEURL1BProteinHetionet hetionet:covaries:150726-54492Inferred only
NICOL1 covaries with FBXO41ProteinHetionet hetionet:covaries:150726-401115Inferred only
FBXO41 covaries with NKX2-1ProteinHetionet hetionet:covaries:150726-7080Inferred only
FBXO41 covaries with R3HDM4ProteinHetionet hetionet:covaries:150726-91300Inferred only
FBXO41 covaries with RBM38ProteinHetionet hetionet:covaries:150726-55544Inferred only

Show the remaining 13

FBXO41 covaries with SPRED3ProteinHetionet hetionet:covaries:150726-399473Inferred only
FBXO41 covaries with VPS4AProteinHetionet hetionet:covaries:150726-27183Inferred only
FBXO41 covaries with XAB2ProteinHetionet hetionet:covaries:150726-56949Inferred only
FBXO41 covaries with ZNF660ProteinHetionet hetionet:covaries:150726-285349Inferred only
DISC1 interacts with FBXO41ProteinHetionet hetionet:interacts:150726-27185Inferred only
SKP1 interacts with FBXO41ProteinHetionet hetionet:interacts:150726-6500Inferred only
FBXO41 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
FBXO41 participates in Antigen processing: Ubiquitination & Proteasome degradationPathwayReactome R-HSA-983168Inferred only
FBXO41 participates in Class I MHC mediated antigen processing & presentationPathwayReactome R-HSA-983169Inferred only
FBXO41 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
FBXO41 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
FBXO41 participates in NeddylationPathwayReactome R-HSA-8951664Inferred only
FBXO41 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only

Other names

3 names

Resolves to: FBXO41

Also called: F-box only protein 41FBX41KIAA1940

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