Pathway
N-Glycan antennae elongation
N-glycans are further modified after the commitment to Complex or Hybrid N-glycans. The exact structure of the network of metabolic reactions involved is complex and not yet validated experimentally. Here we will show a generic reaction for each of the genes known to be involved in N-Glycosylation.
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For a better annotation of the reactions and genes involved in the synthesis of Complex and Hybrid N-glycans we recommend the GlycoGene Database (Ito H. et al, 2010) (http://riodb.ibase.aist.go.jp/rcmg/ggdb/textsearch.jsp) for annotations of genes, and the Consortium for Functional Genomics (http://riodb.ibase.aist.go.jp/rcmg/ggdb/textsearch.jsp) for annotation of Glycan structures and reactions. Moreover, a computationally inferred prediction for the structure of this network is available through the software GlycoVis (Hossler P. et. al. 2006).
What the reference databases state
Statements
15 statements
15 statements · 1 reference database · Subject: N-Glycan antennae elongation · Sources: Reactome
- B4GALT1 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- B4GALT2 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- B4GALT3 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- B4GALT4 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- B4GALT5 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- B4GALT6 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- MGAT4A participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- MGAT4B participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- MGAT4C participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- MGAT5 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- ST3GAL4 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- ST6GAL1 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
Show the remaining 3
- ST8SIA2 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- ST8SIA3 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only
- ST8SIA6 participates in N-Glycan antennae elongationProteinReactome R-HSA-975577Inferred only