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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Proteins
Interactions
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Reach

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Organisms
Materials
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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Pathways

Names from Reactome and WikiPathways

pathways in the graph: 3,812

Filter pathways by name

#a b c d e f g h i j k l m n o p q r s t u v w x y z

322 of 3,812 begin with R

RA biosynthesis pathwayReactomeR-HSA-5365859
RAB GEFs exchange GTP for GDP on RABsReactomeR-HSA-8876198
RAB geranylgeranylationReactomeR-HSA-8873719
Rab regulation of traffickingReactomeR-HSA-9007101
RAC1 GTPase cycleReactomeR-HSA-9013149
RAC1 PAK1 p38 MMP2 pathway

More of the reference layer

Biological processes
Anatomy
Cell types
Organisms
Materials
Regulatory assessments
Diseases

Evidence: Compounds · Outcomes · Papers · Search

WikiPathways3303

RAC2 GTPase cycleReactomeR-HSA-9013404

RAC3 GTPase cycleReactomeR-HSA-9013423

RAF activationReactomeR-HSA-5673000

RAF-independent MAPK1/3 activationReactomeR-HSA-112409

RAF/MAP kinase cascadeReactomeR-HSA-5673001

RalA downstream regulated genesWikiPathways2290

RANKL RANK signalingWikiPathways2018

Rap1 signallingReactomeR-HSA-392517

Ras activation upon Ca2+ influx through NMDA receptorReactomeR-HSA-442982

RAS GTPase cycle mutantsReactomeR-HSA-9649913

RAS processingReactomeR-HSA-9648002

Ras signalingWikiPathways4223

RAS signaling downstream of NF1 loss-of-function variantsReactomeR-HSA-6802953

Reactions specific to the complex N-glycan synthesis pathwayReactomeR-HSA-975578

Reactions specific to the hybrid N-glycan synthesis pathwayReactomeR-HSA-975574

Receptor Mediated MitophagyReactomeR-HSA-8934903

Receptor-type tyrosine-protein phosphatasesReactomeR-HSA-388844

Recognition and association of DNA glycosylase with site containing an affected purineReactomeR-HSA-110330

Recognition and association of DNA glycosylase with site containing an affected pyrimidineReactomeR-HSA-110328

Recognition of DNA damage by PCNA-containing replication complexReactomeR-HSA-110314

Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaksReactomeR-HSA-5693565

Recruitment of mitotic centrosome proteins and complexesReactomeR-HSA-380270

Recruitment of NuMA to mitotic centrosomesReactomeR-HSA-380320

Recycling of bile acids and saltsReactomeR-HSA-159418

Recycling of eIF2:GDPReactomeR-HSA-72731

Recycling pathway of L1ReactomeR-HSA-437239

Reduction of cytosolic Ca++ levelsReactomeR-HSA-418359

Reelin signalling pathwayReactomeR-HSA-8866376

Regorafenib-resistant KIT mutantsReactomeR-HSA-9669929

Regorafenib-resistant PDGFR mutantsReactomeR-HSA-9674403

Regucalcin in proximal tubule epithelial kidney cellsWikiPathways4838

Regulated NecrosisReactomeR-HSA-5218859

Regulated proteolysis of p75NTRReactomeR-HSA-193692

Regulation by c-FLIPReactomeR-HSA-3371378

Regulation by TREX1ReactomeR-HSA-3248023

Regulation of actin cytoskeletonWikiPathways51

Regulation of actin dynamics for phagocytic cup formationReactomeR-HSA-2029482

Regulation of activated PAK-2p34 by proteasome mediated degradationReactomeR-HSA-211733

Regulation of APC/C activators between G1/S and early anaphaseReactomeR-HSA-176408

Regulation of ApoptosisReactomeR-HSA-169911

Regulation of BACH1 activityReactomeR-HSA-9708530

Regulation of beta-cell developmentReactomeR-HSA-186712

Regulation of CDH1 Expression and FunctionReactomeR-HSA-9764265

Regulation of CDH1 FunctionReactomeR-HSA-9764561

Regulation of CDH1 Gene TranscriptionReactomeR-HSA-9764560

Regulation of CDH1 mRNA translation by microRNAsReactomeR-HSA-9764562

Regulation of CDH1 posttranslational processing and trafficking to plasma membraneReactomeR-HSA-9768727

Regulation of CDH11 Expression and FunctionReactomeR-HSA-9759475

Regulation of CDH11 functionReactomeR-HSA-9762292

Regulation of CDH11 gene transcriptionReactomeR-HSA-9762293

Regulation of CDH11 mRNA translation by microRNAsReactomeR-HSA-9759811

Regulation of CDH19 Expression and FunctionReactomeR-HSA-9764302

Regulation of cholesterol biosynthesis by SREBP (SREBF)ReactomeR-HSA-1655829

Regulation of clotting cascadeReactomeR-HSA-9769739

Regulation of commissural axon pathfinding by SLIT and ROBOReactomeR-HSA-428542

Regulation of Complement cascadeReactomeR-HSA-977606

Regulation of cortical dendrite branchingReactomeR-HSA-8985801

Regulation of cytoskeletal remodeling and cell spreading by IPP complex componentsReactomeR-HSA-446388

Regulation of cytotoxic T cell responses by Malat1 miR 15 16 circuit WikiPathways5489

Regulation of endogenous retroelementsReactomeR-HSA-9842860

Regulation of endogenous retroelements by KRAB-ZFP proteinsReactomeR-HSA-9843940

Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)ReactomeR-HSA-9845323

Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complexReactomeR-HSA-9843970

Regulation of Expression and Function of Type I Classical CadherinsReactomeR-HSA-9764274

Regulation of Expression and Function of Type II Classical CadherinsReactomeR-HSA-9764260

Regulation of expression of SLITs and ROBOsReactomeR-HSA-9010553

Regulation of FOXO transcriptional activity by acetylationReactomeR-HSA-9617629

Regulation of FXIIa and plasma kallikrein activityReactomeR-HSA-9855719

Regulation of FZD by ubiquitinationReactomeR-HSA-4641263

Regulation of gap junction activityReactomeR-HSA-191650

Regulation of GBP-mediated host defenseReactomeR-HSA-9968551

Regulation of gene expression by Hypoxia-inducible FactorReactomeR-HSA-1234158

Regulation of gene expression in beta cellsReactomeR-HSA-210745

Regulation of gene expression in early pancreatic precursor cellsReactomeR-HSA-210747

Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cellsReactomeR-HSA-210746

Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cellsReactomeR-HSA-210744

Regulation of Glucokinase by Glucokinase Regulatory ProteinReactomeR-HSA-170822

Regulation of glycolysis by fructose 2,6-bisphosphate metabolismReactomeR-HSA-9634600

Regulation of HMOX1 expression and activityReactomeR-HSA-9707587

Regulation of Homotypic Cell-Cell AdhesionReactomeR-HSA-9759476

Regulation of HSF1-mediated heat shock responseReactomeR-HSA-3371453

Regulation of IFNA/IFNB signalingReactomeR-HSA-912694

Regulation of IFNG signalingReactomeR-HSA-877312

Regulation of innate immune responses to cytosolic DNAReactomeR-HSA-3134975

Regulation of insulin secretionReactomeR-HSA-422356

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)ReactomeR-HSA-381426

Regulation of KIT signalingReactomeR-HSA-1433559

Regulation of lipid metabolism by PPARalphaReactomeR-HSA-400206

Regulation of localization of FOXO transcription factorsReactomeR-HSA-9614399

Regulation of MECP2 expression and activityReactomeR-HSA-9022692

Regulation of MITF-M dependent genes involved in invasionReactomeR-HSA-9854909

Regulation of MITF-M dependent genes involved in metabolismReactomeR-HSA-9854907

Regulation of MITF-M-dependent genes involved in apoptosisReactomeR-HSA-9824594

Regulation of MITF-M-dependent genes involved in cell cycle and proliferationReactomeR-HSA-9825892

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