Pathway
RAS processing
RAS proteins undergo several processing steps during maturation including farnesylation, carboxy-terminal cleavage and carboxymethylation, among others. These steps are required for their membrane localization and function and ultimately for their ability to activate RAF (reviewed in Gysin et al, 2011; Ahearn et al, 2018).
REACT:R-HSA-9648002Reactome
What the reference databases state
Statements
24 statements
24 statements · 1 reference database · Subject: RAS processing · Sources: Reactome
- ABHD17A participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- ABHD17B participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- ABHD17C participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- ARL2 participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- BCL2L1 participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- CALM1 participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- FNTA participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- FNTB participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- GOLGA7 participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- HRAS participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- ICMT participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- KRAS participates in RAS processingProteinReactome R-HSA-9648002Inferred only
Show the remaining 12
- LYPLA1 participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- NRAS participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- PDE6D participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- PRKCQ participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- PRKG2 participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- RCE1 participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- RPS27A participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- UBA52 participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- UBB participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- UBC participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- USP17L2 participates in RAS processingProteinReactome R-HSA-9648002Inferred only
- ZDHHC9 participates in RAS processingProteinReactome R-HSA-9648002Inferred only