Pathway
RA biosynthesis pathway
The major activated retinoid, all-trans-retinoic acid (atRA) is produced by the dehydrogenation of all-trans-retinol (atROL) by members of the short chain dehydrogenase/reductase (SDR) and aldehyde dehydrogenase (RALDH) gene families.
REACT:R-HSA-5365859Reactome
What the reference databases state
Statements
22 statements
22 statements · 1 reference database · Subject: RA biosynthesis pathway · Sources: Reactome
- ADH1A participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- ADH1C participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- ADH4 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- AKR1C3 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- ALDH1A1 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- ALDH1A2 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- ALDH1A3 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- ALDH8A1 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- CRABP1 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- CYP26A1 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- CYP26B1 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- CYP26C1 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
Show the remaining 10
- DHRS3 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- DHRS4 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- DHRS9 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- RDH10 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- RDH11 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- RDH13 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- RDH14 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- RDH16 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- RDH5 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only
- SDR16C5 participates in RA biosynthesis pathwayProteinReactome R-HSA-5365859Inferred only