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Reach

sn-glycerol 3-phosphocholine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

323 compounds within 3 steps: 8 in 1, 35 in 2, 280 in 3

Does it reach a compound?

Three steps

(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
hexadecanoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
3. 1-hexadecanoyl-sn-glycero-3-phosphate + H2O = sn-glycerol 3-phosphate + hexadecanoate + H(+)
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 4 morecytosol
thio-Mo-molybdopterinReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by GPCPD1, CHDH, MOCOScytosol
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 2 morecytosol
1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. phosphocholine + CTP + H(+) = CDP-choline + diphosphate
3. 1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-choline = 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)
Catalysed by ENPP6, PCYT1A, PCYT1B, CEPT1
(5Z)-tetradecenoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by GPCPD1, CHAT, SLC27A2, ACSL4 and 6 morecytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by GPCPD1, CHAT, ACADM, ECHS1 and 2 morecytosol, mitochondrial matrix
2-glyceryl-prostaglandin H2Reach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. 2-glyceryl-prostaglandin G2 + AH2 = 2-glyceryl-prostaglandin H2 + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by GPCPD1, CHAT, HADHA, ACAA2 and 1 morecytosol, mitochondrial matrix
(7Z)-hexadecenoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by GPCPD1, CHAT, SLC27A2, ACSL4 and 6 morecytosolOne of 8 routes
tricosanoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by GPCPD1, CHAT, SLC27A2, ACSL4 and 6 morecytosolOne of 4 routes
prostaglandin H1Reach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. prostaglandin G1 + AH2 = prostaglandin H1 + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
(5S,11R)-dihydroxy-(6E,8Z,12E,14Z)-eicosatetraenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,11R)-dihydroxy-(6E,8Z,12E,14Z)-eicosatetraenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
(5S,15R)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,15R)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
(5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
(18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
(15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
(11R)-hydroxy-(5Z,8Z,12E,14Z,17Z)-eicosapentaenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z,17Z)-eicosapentaenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + O2 = 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS2cytosol
(13S)-hydroxy-(9Z,11E)-octadecadienoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (13S)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS1, PTGS2cytosol

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