CHEBI:15978
362,296 routes · scope human · up to 3 steps · built 6 October 2026 · Reactions · API
624 compounds within 3 steps: 11 in 1, 138 in 2, 475 in 3
Three steps
- glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
- 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
- 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate
- glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
- 1-hexadecanoyl-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-sn-glycerol + phosphate
- 1-hexadecanoyl-sn-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerolReach from here →
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 2 morecytosol, mitochondrial matrix
- 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 2 morecytosol, mitochondrial matrix
- glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
- 1-hexadecanoyl-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-sn-glycerol + phosphate
- 1-hexadecanoyl-sn-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- acyl-CoA:sphingosine N-acyltransferase
- 1-O-alkylglycerol + an acyl-CoA = 1-O-alkyl-3-acylglycerol + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 6 morecytosol, Golgi apparatus
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
- ELOVL fatty acid elongase (trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 9 morecytosol, endoplasmic reticulumOne of 2 routes
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- Carnitine O-Palmitoyltransferase
- carnitine O-palmitoyltransferase (dodecanoylcarnitine)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 3 morecytosolOne of 11 routes
- glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
- 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA
- 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + phosphate
- glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
- 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
- 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- long-chain-fatty-acid-CoA ligase (adrenic acid)
- (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA hydrolase
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 10 morecytosolOne of 2 routes
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- fatty-acid-CoA ligase
- peroxisomal acyl-CoA thioesterase
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 2 morecytosol, peroxisomeOne of 2 routes
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- acyl-CoA:sphingosine N-acyltransferase
- a 3-acyl-sn-glycerol + an acyl-CoA = a 1,3-diacyl-sn-glycerol + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 5 morecytosol, Golgi apparatusOne of 2 routes
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- acyl-CoA:sphingosine N-acyltransferase
- a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 6 morecytosol, Golgi apparatus
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- acyl-CoA:sphingosine N-acyltransferase
- a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 5 morecytosol, Golgi apparatus
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 2 morecytosol, mitochondrial matrix
- sn-Glycerol-3-phosphate:(acceptor) 2-oxidoreductase
- glyceronephosphate O-acyltransferase (DHAP)
- 1-hexadecanoylglycerone 3-phosphate + hexadecan-1-ol = 1-O-hexadecylglycerone 3-phosphate + hexadecanoate + H(+)
Catalysed by GPD2, GNPAT, AGPSmitochondrial matrix, peroxisome
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- long-chain-fatty-acid-CoA ligase (palmitolate)
- medium-chain acyl-CoA dehydrogenase (palmitoleoyl-CoA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 12 morecytosol, mitochondrial matrixOne of 3 routes
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- long-chain-fatty-acid-CoA ligase (margaric acid)
- medium-chain acyl-CoA dehydrogenase (heptadecanoyl-CoA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 12 morecytosol, mitochondrial matrixOne of 2 routes
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- Transport of octadecenoyl-CoA into Mitochondrial Matrix
- medium-chain acyl-CoA dehydrogenase (oleoyl-CoA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 7 morecytosol, mitochondrial matrixOne of 2 routes
- glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
- 1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
- 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoate + H(+)
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- acyl-CoA:sphingosine N-acyltransferase
- N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 5 morecytosol, Golgi apparatus
- glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
- 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
- 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + octadecanoate + H(+)
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- N-acetylglutamate synthase (N-acetyl-L-cysteine)
- Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 2 morecytosol, mitochondrial matrix
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- long-chain-fatty-acid-CoA ligase (stearate)
- Acyl-CoA:cholesterol O-acyltransferase
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 9 morecytosol, endoplasmic reticulumOne of 2 routes
- glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
- (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
- 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- cholate-CoA ligase (3alpha,12alpha-dihydroxy-5beta-cholanate)
- deoxycholoyl-CoA to glycodeoxycholate conversion
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 2 morecytosolOne of 3 routes
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- acyl-CoA:sphingosine N-acyltransferase
- sphing-4-enine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = sphinga-4E,14Z-dienine + 2 Fe(III)-[cytochrome b5] + 2 H2O
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 5 morecytosol, Golgi apparatus
- glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
- long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
- 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + CoA