Papers/PMID:35134311
Effect of Nicotinamide in Skin Cancer and Actinic Keratoses Chemoprophylaxis, and Adverse Effects Related to Nicotinamide: A Systematic Review and Meta-Analysis.
Journal of cutaneous medicine and surgery2022The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
nicotinamide — no detected effect on melanoma incidence
StrongEvidence strength: strong. Randomised human trials or their synthesis, with the effect's size and interval recorded and no recorded weakness outstanding.FindingNull result“No difference in risk of melanoma was observed with nicotinamide compared to control (RR 0.89 (95% CI, 0.29-2.79; I 2 = 0%; 416 patients; 2 trials)).”
Quoted verbatim from Effect of Nicotinamide in Skin Cancer and Actinic Keratoses Chemoprophylaxis, and Adverse Effects Related to Nicotinamide: A Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Participants
- 416
- Population
- Pooled randomised trials of nicotinamide versus control, mainly tertiary skin-cancer prevention populations (2 trials)
Effect 0.89 risk ratio, 95% CI 0.29 to 2.79
Effect of Nicotinamide in Skin Cancer and Actinic Keratoses Chemoprophylaxis, and Adverse Effects Related to Nicotinamide: A Systematic Review and Meta-Analysis.2022PMID:35134311Permalink