Proteins/UNIPROT:P31321

PRKAR1B

ProteinUNIPROT:P31321

Open in the graph

Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells..

Function from UniProtKB (P31321), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

Marbach-Schaaf neurodevelopmental syndrome has a germline basis in PRKAR1BDiseaseGenCC HGNC:9390|MONDO:0859214Inferred only
PRKAR1B-related neurodegenerative dementia with intermediate filaments has a germline basis in PRKAR1BDiseaseGenCC HGNC:9390|MONDO:0018475Inferred only

Statements

107 statements

107 statements · 4 reference databases · Subject: PRKAR1B · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

GPER1 covaries with PRKAR1BProteinHetionet hetionet:covaries:2852-5575Inferred only
SLC45A4 covaries with PRKAR1BProteinHetionet hetionet:covaries:5575-57210Inferred only
PRKAR1B interacts with AKAP1ProteinHetionet hetionet:interacts:5575-8165Inferred only
PRKAR1B interacts with CUL3ProteinHetionet hetionet:interacts:5575-8452Inferred only
EGFR interacts with PRKAR1BProteinHetionet hetionet:interacts:1956-5575Inferred only
PRKAR1B interacts with PPP1R9AProteinHetionet hetionet:interacts:55607-5575Inferred only
PRKAR1A interacts with PRKAR1BProteinHetionet hetionet:interacts:5573-5575Inferred only
SMAD3 interacts with PRKAR1BProteinHetionet hetionet:interacts:4088-5575Inferred only
SMAD4 interacts with PRKAR1BProteinHetionet hetionet:interacts:4089-5575Inferred only
PRKAR1B interacts with THG1LProteinHetionet hetionet:interacts:54974-5575Inferred only
PRKAR1B interacts with UBCProteinHetionet hetionet:interacts:5575-7316Inferred only
PRKAR1B interacts with UBE2IProteinHetionet hetionet:interacts:5575-7329Inferred only

Show the remaining 95

PRKAR1B interacts with WNK1ProteinHetionet hetionet:interacts:5575-65125Inferred only
PRKAR1B interacts with WRNProteinHetionet hetionet:interacts:5575-7486Inferred only
PRKAR1B participates in Activation of NMDA receptors and postsynaptic eventsPathwayReactome R-HSA-442755Inferred only
PRKAR1B participates in ADORA2B mediated anti-inflammatory cytokines productionPathwayReactome R-HSA-9660821Inferred only
PRKAR1B participates in Albuterol and budesonide therapy for asthmaPathwayWikiPathways WP5503Inferred only
PRKAR1B participates in Anti-inflammatory response favouring Leishmania parasite infectionPathwayReactome R-HSA-9662851Inferred only
PRKAR1B participates in Aquaporin-mediated transportPathwayReactome R-HSA-445717Inferred only
PRKAR1B participates in Ca-dependent eventsPathwayReactome R-HSA-111996Inferred only
PRKAR1B participates in Calcium regulation in cardiac cellsPathwayWikiPathways WP536Inferred only
PRKAR1B participates in Calmodulin induced eventsPathwayReactome R-HSA-111933Inferred only
PRKAR1B participates in CaM pathwayPathwayReactome R-HSA-111997Inferred only
PRKAR1B participates in Cannabinoid receptor signalingPathwayWikiPathways WP3869Inferred only
PRKAR1B participates in Cellular responses to mechanical stimuliPathwayReactome R-HSA-9855142Inferred only
PRKAR1B participates in Cellular responses to stimuliPathwayReactome R-HSA-8953897Inferred only
PRKAR1B participates in CREB1 phosphorylation through the activation of Adenylate CyclasePathwayReactome R-HSA-442720Inferred only
PRKAR1B participates in DAG and IP3 signalingPathwayReactome R-HSA-1489509Inferred only
PRKAR1B participates in DARPP-32 eventsPathwayReactome R-HSA-180024Inferred only
PRKAR1B participates in DiseasePathwayReactome R-HSA-1643685Inferred only
PRKAR1B participates in EPAC1 and PKA reduction of retinal inflammationPathwayWikiPathways WP5440Inferred only
PRKAR1B participates in Factors involved in megakaryocyte development and platelet productionPathwayReactome R-HSA-983231Inferred only
PRKAR1B participates in FCGR3A-mediated IL10 synthesisPathwayReactome R-HSA-9664323Inferred only
PRKAR1B participates in G alpha (i) signalling eventsPathwayReactome R-HSA-418594Inferred only
PRKAR1B participates in G alpha (s) signalling eventsPathwayReactome R-HSA-418555Inferred only
PRKAR1B participates in G protein signalingPathwayWikiPathways WP35Inferred only
PRKAR1B participates in G-protein mediated eventsPathwayReactome R-HSA-112040Inferred only
PRKAR1B participates in Glucagon signaling in metabolic regulationPathwayReactome R-HSA-163359Inferred only
PRKAR1B participates in Glucagon-like Peptide-1 (GLP1) regulates insulin secretionPathwayReactome R-HSA-381676Inferred only
PRKAR1B participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
PRKAR1B participates in GPER1 signalingPathwayReactome R-HSA-9634597Inferred only
PRKAR1B participates in Hedgehog 'off' statePathwayReactome R-HSA-5610787Inferred only
PRKAR1B participates in HemostasisPathwayReactome R-HSA-109582Inferred only
PRKAR1B participates in High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cellsPathwayReactome R-HSA-9856530Inferred only
PRKAR1B participates in Hippo Merlin signaling dysregulationPathwayWikiPathways WP4541Inferred only
PRKAR1B participates in Hippo signaling regulationPathwayWikiPathways WP4540Inferred only
PRKAR1B participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
PRKAR1B participates in Integration of energy metabolismPathwayReactome R-HSA-163685Inferred only
PRKAR1B participates in Intracellular signaling by second messengersPathwayReactome R-HSA-9006925Inferred only
PRKAR1B participates in Leishmania infectionPathwayReactome R-HSA-9658195Inferred only
PRKAR1B participates in Leishmania parasite growth and survivalPathwayReactome R-HSA-9664433Inferred only
PRKAR1B participates in Lipid metabolism pathwayPathwayWikiPathways WP3965Inferred only
PRKAR1B participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
PRKAR1B participates in Myometrial relaxation and contraction pathwaysPathwayWikiPathways WP289Inferred only
PRKAR1B participates in Neuronal SystemPathwayReactome R-HSA-112316Inferred only
PRKAR1B participates in Neurotransmitter receptors and postsynaptic signal transmissionPathwayReactome R-HSA-112314Inferred only
PRKAR1B participates in Opioid SignallingPathwayReactome R-HSA-111885Inferred only
PRKAR1B participates in Parasitic Infection PathwaysPathwayReactome R-HSA-9824443Inferred only
PRKAR1B participates in PKA activationPathwayReactome R-HSA-163615Inferred only
PRKAR1B participates in PKA activation in glucagon signallingPathwayReactome R-HSA-164378Inferred only
PRKAR1B participates in PKA-mediated phosphorylation of CREBPathwayReactome R-HSA-111931Inferred only
PRKAR1B participates in PLC beta mediated eventsPathwayReactome R-HSA-112043Inferred only
PRKAR1B participates in Post NMDA receptor activation eventsPathwayReactome R-HSA-438064Inferred only
PRKAR1B participates in Regulation of insulin secretionPathwayReactome R-HSA-422356Inferred only
PRKAR1B participates in Response of endothelial cells to shear stressPathwayReactome R-HSA-9860931Inferred only
PRKAR1B participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
PRKAR1B participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
PRKAR1B participates in Signaling by HedgehogPathwayReactome R-HSA-5358351Inferred only
PRKAR1B participates in Sudden infant death syndrome SIDS susceptibility pathwaysPathwayWikiPathways WP706Inferred only
PRKAR1B participates in Transmission across Chemical SynapsesPathwayReactome R-HSA-112315Inferred only
PRKAR1B participates in Transport of small moleculesPathwayReactome R-HSA-382551Inferred only
PRKAR1B participates in Vasopressin regulates renal water homeostasis via AquaporinsPathwayReactome R-HSA-432040Inferred only
PRKAR1B regulates negative regulation of cAMP/PKA signal transductionBiological processgene ontology P31321|GO:0141162Inferred only
PRKAR1B regulates negative regulation of inflammatory response to antigenic stimulusBiological processgene ontology P31321|GO:0002862Inferred only
PRKAR1B regulates positive regulation of excitatory postsynaptic potentialBiological processgene ontology P31321|GO:2000463Inferred only
PRKAR1B regulates positive regulation of fear responseBiological processgene ontology P31321|GO:1903367Inferred only
PRKAR1B regulates positive regulation of long-term synaptic potentiationBiological processgene ontology P31321|GO:1900273Inferred only
PRKAR1B regulates regulation of synaptic vesicle cycleBiological processgene ontology P31321|GO:0098693Inferred only
PRKAR1B decreases the expression of ALDOAProteinHetionet hetionet:regulates:5575-226Inferred only
PRKAR1B increases the expression of BACE2ProteinHetionet hetionet:regulates:5575-25825Inferred only
PRKAR1B increases the expression of CADM1ProteinHetionet hetionet:regulates:5575-23705Inferred only
PRKAR1B decreases the expression of CANT1ProteinHetionet hetionet:regulates:5575-124583Inferred only
PRKAR1B increases the expression of CASP2ProteinHetionet hetionet:regulates:5575-835Inferred only
PRKAR1B decreases the expression of CCDC86ProteinHetionet hetionet:regulates:5575-79080Inferred only
PRKAR1B increases the expression of CDK6ProteinHetionet hetionet:regulates:5575-1021Inferred only
PRKAR1B increases the expression of CEMIP2ProteinHetionet hetionet:regulates:5575-23670Inferred only
PRKAR1B increases the expression of CES1ProteinHetionet hetionet:regulates:5575-1066Inferred only
PRKAR1B decreases the expression of CLSTN1ProteinHetionet hetionet:regulates:5575-22883Inferred only
PRKAR1B increases the expression of CPVLProteinHetionet hetionet:regulates:5575-54504Inferred only
PRKAR1B increases the expression of CRIP1ProteinHetionet hetionet:regulates:5575-1396Inferred only
PRKAR1B decreases the expression of CSRP1ProteinHetionet hetionet:regulates:5575-1465Inferred only
PRKAR1B increases the expression of E2F2ProteinHetionet hetionet:regulates:5575-1870Inferred only
PRKAR1B decreases the expression of ENOPH1ProteinHetionet hetionet:regulates:5575-58478Inferred only
PRKAR1B increases the expression of GARRE1ProteinHetionet hetionet:regulates:5575-9710Inferred only
PRKAR1B decreases the expression of HADHProteinHetionet hetionet:regulates:5575-3033Inferred only
PRKAR1B increases the expression of HMGA2ProteinHetionet hetionet:regulates:5575-8091Inferred only
PRKAR1B decreases the expression of HMGCS1ProteinHetionet hetionet:regulates:5575-3157Inferred only
PRKAR1B increases the expression of MCOLN1ProteinHetionet hetionet:regulates:5575-57192Inferred only
PRKAR1B increases the expression of MYBProteinHetionet hetionet:regulates:5575-4602Inferred only
PRKAR1B decreases the expression of PPP2R5EProteinHetionet hetionet:regulates:5575-5529Inferred only
PRKAR1B decreases the expression of PTPROProteinHetionet hetionet:regulates:5575-5800Inferred only
PRKAR1B decreases the expression of RPN1ProteinHetionet hetionet:regulates:5575-6184Inferred only
PRKAR1B increases the expression of RRP8ProteinHetionet hetionet:regulates:5575-23378Inferred only
PRKAR1B decreases the expression of SACM1LProteinHetionet hetionet:regulates:5575-22908Inferred only
PRKAR1B decreases the expression of SDC1ProteinHetionet hetionet:regulates:5575-6382Inferred only
PRKAR1B increases the expression of SERPINA3ProteinHetionet hetionet:regulates:5575-12Inferred only
PRKAR1B increases the expression of WIF1ProteinHetionet hetionet:regulates:5575-11197Inferred only

Other names

1 name

Resolves to: PRKAR1B

Also called: cAMP-dependent protein kinase type I-beta regulatory subunit

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