Proteins/UNIPROT:Q5BKX6

SLC45A4

ProteinUNIPROT:Q5BKX6Polyamine-transporter SLC45A4

Neuronal polyamine-transporter involved in pain perception. Transports polyamines such as putrescine, cadaverine, spermine and spermidine. Expressed in sensory neuron subtypes within the dorsal root ganglion, where it regulates the excitability of C-polymodal nociceptors by mediating polyamine transport (By similarity)..

Function from UniProtKB (Q5BKX6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 3 reference databases · Subject: SLC45A4 · Sources: Bgee, Hetionet, Rhea

Order

SLC45A4 covaries with CTBSProteinHetionet hetionet:covaries:1486-57210Inferred only
SLC45A4 covaries with DIPK1CProteinHetionet hetionet:covaries:125704-57210Inferred only
NOTCH1 covaries with SLC45A4ProteinHetionet hetionet:covaries:4851-57210Inferred only
SLC45A4 covaries with PRKAR1BProteinHetionet hetionet:covaries:5575-57210Inferred only
SLC45A4 covaries with PRPS1L1ProteinHetionet hetionet:covaries:221823-57210Inferred only
SLC45A4 covaries with SNX8ProteinHetionet hetionet:covaries:29886-57210Inferred only
SLC45A4 covaries with TMEM184AProteinHetionet hetionet:covaries:202915-57210Inferred only
SLC45A4 covaries with WDR90ProteinHetionet hetionet:covaries:197335-57210Inferred only
SLC45A4 is expressed in pancreatic ductal cellCell typeBgee ENSG00000022567Inferred only
UBC interacts with SLC45A4ProteinHetionet hetionet:interacts:57210-7316Inferred only
putrescine is transported by SLC45A4CompoundRhea RHEA:72135Inferred only
spermidine is transported by SLC45A4CompoundRhea RHEA:35039Inferred only

Reactions

2 reactions

spermidinespermidine
Transported by SLC22A2 or SLC22A1 or SLC22A3 or SLC45A4 or SLC22A16 or PANX1
Reaction pageDirection not assertedBalanced
Rhea RHEA:35039CC BY 4.0Reference data
putrescineputrescine
Transported by SLC22A2 or SLC22A1 or SLC45A4
Reaction pageDirection not asserted

Other names

3 names

Resolves to: SLC45A4

Also called: KIAA1126Polyamine-transporter SLC45A4Solute carrier family 45 member 4

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