parietal foramina
Findings
No curated finding names parietal foramina yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Enlarged parietal foramina (EPF) is a developmental defect, characterized by variable intramembranous ossification defects of the parietal bones, which is either asymptomatic, symptomatic (headaches, nausea, vomiting, intellectual disability) or associated with other pathologies.
Definition from the Mondo Disease Ontology (MONDO:0018953), read 2026-09-29. CC BY 4.0.
Features
20 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Parietal foraminaHPOHP:0002697
- Very frequent (80% to 99% of cases)
- Abnormal posterior cranial fossa morphologyHPOHP:0000932
- Occasional (5% to 29% of cases)
- HeadacheHPOHP:0002315
- Occasional (5% to 29% of cases)
- Scalp tendernessHPOHP:0100809
- Occasional (5% to 29% of cases)
- Venous malformationHPOHP:0012721
- Occasional (5% to 29% of cases)
- VomitingHPOHP:0002013
- Occasional (5% to 29% of cases)
- Abnormal cerebral vein morphologyHPOHP:0012480
- Very rare (1% to 4% of cases)
- Aplasia cutis congenita of scalpHPOHP:0007385
- Very rare (1% to 4% of cases)
- Broad thumbHPOHP:0011304
- Very rare (1% to 4% of cases)
- Cleft lipHPOHP:0410030
- Very rare (1% to 4% of cases)
- Cleft palateHPOHP:0000175
- Very rare (1% to 4% of cases)
- Congenital craniofacial dysostosisHPOHP:0008497
- Very rare (1% to 4% of cases)
Show the remaining 8
- CraniosynostosisHPOHP:0001363
- Very rare (1% to 4% of cases)
- EncephalomalaciaHPOHP:0040197
- Very rare (1% to 4% of cases)
- Intellectual disabilityHPOHP:0001249
- Very rare (1% to 4% of cases)
- Multiple exostosesHPOHP:0002762
- Very rare (1% to 4% of cases)
- MyelomeningoceleHPOHP:0002475
- Very rare (1% to 4% of cases)
- Occipital encephaloceleHPOHP:0002085
- Very rare (1% to 4% of cases)
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
- Narrower terms (3)
Other names
6 names
Resolves to: parietal foramina
- Also called
- catlin marksenlarged parietal foraminafenestrae parietales symmetricaeforamina parietalia permagnahereditary cranium bifidumsymmetric parietal foramina