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Proteins/UNIPROT:Q8N653
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras GTPases (M-Ras/MRAS, K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS) and Ras-like protein RIT1. Acts as a negative regulator of RAS-MAPK signaling by controlling Ras levels and decreasing Ras association with membranes..
Function from UniProtKB (Q8N653), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
6 rows
145 statements
145 statements · 3 reference databases · Subject: LZTR1 · Sources: gene ontology, Hetionet, WikiPathways
3 names
Resolves to: LZTR1