breast cancer
MONDO:0007254Mondo
Findings
No curated finding names breast cancer yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A primary or metastatic malignant neoplasm involving the breast. The vast majority of cases are carcinomas arising from the breast parenchyma or the nipple. Malignant breast neoplasms occur more frequently in females than in males.
Definition from the Mondo Disease Ontology (MONDO:0007254), read 2026-09-29. CC BY 4.0.
Genes
21 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- BARD1HGNC:952
- Definitive · G2P · Autosomal dominant · 2022
- TP53HGNC:11998
- Definitive · Ambry Genetics · Autosomal dominant · 2018
- ATRIPHGNC:33499
- Moderate · G2P · Autosomal dominant · 2023
- LZTR1HGNC:6742
- Moderate · G2P · Autosomal dominant · 2023
- MAP3K1HGNC:6848
- Moderate · G2P · Autosomal dominant · 2023
- AURKAHGNC:11393
- Limited · Ambry Genetics · Autosomal dominant · 2018
- MSH6HGNC:7329
- Limited · Ambry Genetics · Autosomal dominant · 2022
- NTHL1HGNC:8028
- Limited · Ambry Genetics · Autosomal recessive · 2024
- PMS2HGNC:9122
- Limited · Ambry Genetics · Autosomal dominant · 2022
- RASAL1HGNC:9873
- Limited · Ambry Genetics · Autosomal dominant · 2020
- RECQL5HGNC:9950
- Limited · Ambry Genetics · Autosomal dominant · 2019
- ROS1HGNC:10261
- Limited · Ambry Genetics · Autosomal dominant · 2020
- BLMHGNC:1058
- Disputed Evidence · Ambry Genetics · Autosomal dominant · 2023
- FANCCHGNC:3584
- Disputed Evidence · Ambry Genetics · Autosomal dominant · 2024
- FANCMHGNC:23168
- Disputed Evidence · Ambry Genetics · Autosomal dominant · 2022
- MLH1HGNC:7127
- Disputed Evidence · Ambry Genetics · Autosomal dominant · 2022
- MRE11HGNC:7230
- Disputed Evidence · Ambry Genetics · Autosomal dominant · 2024
- MSH2HGNC:7325
- Disputed Evidence · Ambry Genetics · Autosomal dominant · 2022
- RECQLHGNC:9948
- Disputed Evidence · Ambry Genetics · Autosomal dominant · 2022
- RINT1HGNC:21876
- Disputed Evidence · Ambry Genetics · Autosomal dominant · 2023
- XRCC2HGNC:12829
- Disputed Evidence · Ambry Genetics · Autosomal dominant · 2021
Where it sits
- A kind of
Other names
10 names
Resolves to: breast cancer
- Also called
- cancer of breastmalignant breast neoplasmmalignant breast tumormalignant breast tumourmalignant neoplasm of breastmalignant neoplasm of the breastmalignant tumor of breastmalignant tumor of the breastmalignant tumour of breastmalignant tumour of the breast