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Proteins/UNIPROT:P49916
Isoform 3 functions as a heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as a DNA ligase in mitochondrial base-excision DNA repair..
Function from UniProtKB (P49916), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
83 statements
83 statements · 5 reference databases · Subject: LIG3 · Sources: gene ontology, Hetionet, Reactome, UniProt, WikiPathways
2 names
Resolves to: LIG3