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Proteins/UNIPROT:P48039
High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. Possibly involved in sleep induction, by melatonin activation of the potassium channel KCNMA1/BK and the dissociation of G-beta and G-gamma subunits, thereby decreasing synaptic transmission (By similarity)..
Function from UniProtKB (P48039), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
51 statements
51 statements · 3 reference databases · Subject: MTNR1A · Sources: Hetionet, Reactome, WikiPathways
2 names
Resolves to: MTNR1A