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Proteins/UNIPROT:P35218
Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3. Mitochondria are impermeable to HCO3, and thus this intramitochondrial carbonic anhydrase is pivotal in providing HCO3 for multiple mitochondrial enzymes that catalyze the formation of essential metabolites of intermediary metabolism in the urea and Krebs cycles..
Function from UniProtKB (P35218), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
15 statements
15 statements · 4 reference databases · Subject: CA5A · Sources: Hetionet, Human-GEM, Reactome, UniProt
3 reactions
ATP+water+dodecanoateADP+proton+dodecanoate+phosphate(3-)
Transported by NAE1 or AP1G1 or CA5A
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR00190CC BY 4.0Reference data
4 names
Resolves to: CA5A
Reaction pageReversibleBalancedEC 4.2.1.1mitochondrial matrix
Human-GEM MAR03956CC BY 4.0Reference data
hydrogencarbonate+hydroncarbon dioxide+water
Catalysed by CA12 or CA1 or CA2 or CA4 or CA6 or CA5A or CA7 or CA9 or CA13 or CA14 or CA5B
Reaction pageReversibleBalanced
Rhea RHEA:10748CC BY 4.0Reference data