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Proteins/UNIPROT:Q9UJ41
Acts as a guanine-nucleotide releasing factor (GEF) for RAB5A by promoting the conversion of inactive RAB-GDP to the active form RAB-GTP. Forms a complex with RABEP1 that acts as Rab4/Rab5 effector regulating endosome fusion. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Also functions as a ubiquitin ligase (By similarity)..
Function from UniProtKB (Q9UJ41), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
38 statements
38 statements · 3 reference databases · Subject: RABGEF1 · Sources: Hetionet, Reactome, WikiPathways
4 names
Resolves to: RABGEF1