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Proteins/UNIPROT:P08247

SYP

Protein·UNIPROT:P08247

Open in the graph

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity)..

Function from UniProtKB (P08247), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

2 rows

intellectual disability, X-linked 96 has a germline basis in SYPDiseaseGenCC HGNC:11506|MONDO:0010429Inferred only
non-syndromic X-linked intellectual disability has a germline basis in SYPDiseaseGenCC HGNC:11506|MONDO:0019181Inferred only

Statements

17 statements

17 statements · 4 reference databases · Subject: SYP · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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AP1G1 interacts with SYPProteinHetionet hetionet:interacts:164-6855Inferred only
EPOR interacts with SYPProteinHetionet hetionet:interacts:2057-6855Inferred only
GRB2 interacts with SYPProteinHetionet hetionet:interacts:2885-6855Inferred only
SIAH1 interacts with SYPProteinHetionet hetionet:interacts:6477-6855Inferred only
SIAH2 interacts with SYPProteinHetionet hetionet:interacts:6478-6855Inferred only
VAMP2 interacts with SYPProteinHetionet hetionet:interacts:6844-6855Inferred only
SYP participates in Cell lineage map for neuronal differentiationPathwayWikiPathways WP5417Inferred only
SYP participates in Sensory PerceptionPathwayReactome R-HSA-9709957Inferred only
SYP participates in Sensory processing of soundPathwayReactome R-HSA-9659379Inferred only
SYP participates in Sensory processing of sound by inner hair cells of the cochleaPathwayReactome R-HSA-9662360Inferred only
SYP participates in SNARE complex machinery in exocytosisPathwayWikiPathways WP5621Inferred only
SYP participates in Synaptic vesicle pathwayPathwayWikiPathways WP2267Inferred only

Show the remaining 5

SYP regulates regulation of long-term neuronal synaptic plasticityBiological processgene ontology P08247|GO:0048169Inferred only
SYP regulates regulation of neuronal synaptic plasticityBiological processgene ontology P08247|GO:0048168Inferred only
SYP regulates regulation of opioid receptor signaling pathwayBiological processgene ontology P08247|GO:2000474Inferred only
SYP regulates regulation of short-term neuronal synaptic plasticityBiological processgene ontology P08247|GO:0048172Inferred only
SYP regulates regulation of synaptic vesicle primingBiological processgene ontology P08247|GO:0010807Inferred only

Other names

2 names

Resolves to: SYP

Also called: Major synaptic vesicle protein p38Synaptophysin

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