Pathway
The canonical retinoid cycle in rods (twilight vision)
The retinoid cycle (also referred to as the visual cycle) is the process by which the visual chromophore 11-cis-retinal (11cRAL) is released from light-activated opsins in the form all-trans-retinal and isomerized back to its 11-cis isomer ready for another photoisomerization reaction. This process involves oxidation, reduction and isomerization reactions and take place in the retinal pigment epithelium (RPE) and photoreceptor segments of the eye (von Lintig 2012, Blomhoff & Blomhoff 2006, von Lintig et al. 2010, D'Ambrosio et al. 2011). This section describes the retinoid cycle in rods during dark/twilight conditions.
What the reference databases state
Statements
22 statements
22 statements · 1 reference database · Subject: The canonical retinoid cycle in rods (twilight vision) · Sources: Reactome
- ABCA4 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- CYP4V2 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- DHRS9 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- HSD17B1 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- HSD17B6 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- LRAT participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- MYO7A participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RBP1 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RBP3 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RBP4 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RDH10 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RDH11 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
Show the remaining 10
- RDH12 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RDH16 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RDH5 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RDH8 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RHO participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RLBP1 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- RPE65 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- SDR9C7 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- STRA6 participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only
- TTR participates in The canonical retinoid cycle in rods (twilight vision)ProteinReactome R-HSA-2453902Inferred only