Pathway

Activated NTRK2 signals through PLCG1

Activation of the neurotrophin receptor NTRK2 (TRKB) by BDNF or NTF4 triggers downstream PLCgamma (PLCG1) signaling, resulting in formation of secondary messengers DAG and IP3.

Summary from Reactome (R-HSA-9026527), read 2026-09-23.

REACT:R-HSA-9026527Reactome

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What the reference databases state

Statements

4 statements

4 statements · 1 reference database · Subject: Activated NTRK2 signals through PLCG1 · Sources: Reactome

Order

BDNF participates in Activated NTRK2 signals through PLCG1ProteinReactome R-HSA-9026527Inferred only
NTF4 participates in Activated NTRK2 signals through PLCG1ProteinReactome R-HSA-9026527Inferred only
NTRK2 participates in Activated NTRK2 signals through PLCG1ProteinReactome R-HSA-9026527Inferred only
PLCG1 participates in Activated NTRK2 signals through PLCG1ProteinReactome R-HSA-9026527Inferred only