Pathway
Activation of NLRP3 inflammasome by SARS CoV 2
Orf3a from SARS-CoV has been shown to bind TRAF3 and activate the NLRP3 inflammasome. The activation occurs at two points. First, by ubiquinating NF-kB (p105) to stimulate its proteolytic processin...
WP:4876
What the reference databases state
Statements
7 statements
7 statements · 1 reference database · Subject: Activation of NLRP3 inflammasome by SARS CoV 2 · Sources: WikiPathways
- CASP1 participates in Activation of NLRP3 inflammasome by SARS CoV 2ProteinWikiPathways WP4876Inferred only
- IL1B participates in Activation of NLRP3 inflammasome by SARS CoV 2ProteinWikiPathways WP4876Inferred only
- NFKB1 participates in Activation of NLRP3 inflammasome by SARS CoV 2ProteinWikiPathways WP4876Inferred only
- NLRP3 participates in Activation of NLRP3 inflammasome by SARS CoV 2ProteinWikiPathways WP4876Inferred only
- PYCARD participates in Activation of NLRP3 inflammasome by SARS CoV 2ProteinWikiPathways WP4876Inferred only
- RELA participates in Activation of NLRP3 inflammasome by SARS CoV 2ProteinWikiPathways WP4876Inferred only
- TRAF3 participates in Activation of NLRP3 inflammasome by SARS CoV 2ProteinWikiPathways WP4876Inferred only