Pathway
Abacavir transmembrane transport
Cytosolic levels of abacavir are determined by the balance of its facilitated diffusion into the cell mediated by organic cation transporters SLC22A1, 2, and 3, and its ATP-dependent efflux from cells mediated by ABCG2 and ABCB1.
REACT:R-HSA-2161517Reactome
What the reference databases state
Statements
5 statements
5 statements · 1 reference database · Subject: Abacavir transmembrane transport · Sources: Reactome
- ABCB1 participates in Abacavir transmembrane transportProteinReactome R-HSA-2161517Inferred only
- ABCG2 participates in Abacavir transmembrane transportProteinReactome R-HSA-2161517Inferred only
- SLC22A1 participates in Abacavir transmembrane transportProteinReactome R-HSA-2161517Inferred only
- SLC22A2 participates in Abacavir transmembrane transportProteinReactome R-HSA-2161517Inferred only
- SLC22A3 participates in Abacavir transmembrane transportProteinReactome R-HSA-2161517Inferred only