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1,2-dioctanoyl-sn-glycerol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

13 compounds within 3 steps: 1 in 1, 4 in 2, 8 in 3

Does it reach a compound?

One step

1,2-dioctanoyl-sn-glycero-3-phosphocholineReach from here →
1. 1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
Catalysed by CHPT1, CEPT1

Two steps

2-octanoyl-sn-glycero-3-phosphocholineReach from here →
1. 1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
2. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-octanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl octanoate + apo--[retinol-binding protein]
Catalysed by CHPT1, CEPT1, LRAT
all-trans-retinyl octanoateReach from here →
1. 1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
2. 1,2-dioctanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-octanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl octanoate + apo--[retinol-binding protein]
Catalysed by CHPT1, CEPT1, LRAT

Three steps

CHEBI:1146900Reach from here →
Catalysed by CHPT1, CEPT1, ENPP2, CHATcytosolOne of 2 routes
acetylcholineReach from here →

cholineReach from here →

1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)

Catalysed by CHPT1, CEPT1, ENPP2

1,2-dioctanoyl-sn-glycero-3-phosphateReach from here →

1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)

Catalysed by CHPT1, CEPT1, ENPP2

Catalysed by CHPT1, CEPT1, ENPP2, CHATcytosolOne of 3 routes

betaine aldehydeReach from here →

1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
choline dehydrogenase (choline)

Catalysed by CHPT1, CEPT1, ENPP2, CHDHcytosolOne of 3 routes

AH2Reach from here →

1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
choline + A = betaine aldehyde + AH2

Catalysed by CHPT1, CEPT1, ENPP2, CHDH

CHEBI:18132Reach from here →

1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
ATP:choline phosphotransferase

Catalysed by CHPT1, CEPT1, ENPP2, CHKA and 1 morecytosol

chlorine(.)Reach from here →

1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
transport of chloride and choline (cytosol to extracellular)

Catalysed by CHPT1, CEPT1, ENPP2, SLC5A7extracellular space, cytosol

phosphocholineReach from here →

1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
phosphocholine + H2O = choline + phosphate

Catalysed by CHPT1, CEPT1, ENPP2, PHOSPHO1One of 2 routes

an acylcholineReach from here →

1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)
an acylcholine + H2O = a carboxylate + choline + H(+)

Catalysed by CHPT1, CEPT1, ENPP2, BCHE