3-oxoeicosanoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

298 compounds within 3 steps: 1 in 1, 42 in 2, 255 in 3

Three steps

(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. Stearoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 6 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. Stearoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 8 routes
heptadecanoyl-CoAReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. Stearoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 7 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. Stearoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 6 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. Stearoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 6 routes
1-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 3 moreperoxisome
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 10 moreperoxisome
1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 4 moreperoxisome
1-heptadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-heptadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-heptadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, GPAT3, GPAT2 and 6 moreperoxisome, cytosolOne of 2 routes
(6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = (6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 3 moreperoxisome
1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-eicosanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-tetradecanoyl-sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 3 moreperoxisome
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serineReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 3 moreperoxisome
a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-acyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 3 moreperoxisome
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 3 moreperoxisome
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
nonadecanoyl-CoAReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. Stearoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 7 routes
a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
3. (11Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACAA1, MYO5B, SCD, AGPAT2 and 1 moreperoxisome, cytosol
1'-[1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z)-octadecenoyl-CoA = 1'-[1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z)-octadecenoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA = 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA = 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. Stearoyl-CoA hydrolase
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + octadecanoate + H(+)
Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 4 moreperoxisome, cytosol
a 2,3-diacyl-sn-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. acyl-CoA pool formation and breakdown
3. a 2-acylglycerol + an acyl-CoA = a 2,3-diacyl-sn-glycerol + CoA
Catalysed by ACAA1, MYO5B, MOGAT2, MOGAT1peroxisome, cytosol
1-octadecanoyl-sn-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
3. 1-octadecanoyl-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycerol + phosphate
Catalysed by ACAA1, MYO5B, GPAT3, GPAT2 and 3 moreperoxisome, cytosol
1-dodecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-dodecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-tetradecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-(9Z,12Z,15Z-octadecatrienoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z,15Z-octadecatrienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by ACAA1, MYO5B, LPGAT1, PLA2G4Aperoxisome
1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z,12Z-octadecadienoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
decyl (9Z)-octadecenoateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. decan-1-ol + (9Z)-octadecenoyl-CoA = decyl (9Z)-octadecenoate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
hexadecyl (9Z)-octadecenoateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. hexadecan-1-ol + (9Z)-octadecenoyl-CoA = hexadecyl (9Z)-octadecenoate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-O-(9Z)-hexadecenyl (9Z)-octadecenoateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. (9Z)-hexadecen-1-ol + (9Z)-octadecenoyl-CoA = 1-O-(9Z)-hexadecenyl (9Z)-octadecenoate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
octadecyl (9Z)-octadecenoateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. octadecan-1-ol + (9Z)-octadecenoyl-CoA = octadecyl (9Z)-octadecenoate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisomeOne of 2 routes
1-O-(9Z)-octadecenyl (9Z)-octadecenoateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. (9Z)-octadecen-1-ol + (9Z)-octadecenoyl-CoA = 1-O-(9Z)-octadecenyl (9Z)-octadecenoate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-O-eicosanyl (9Z)-octadecenoateReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. eicosan-1-ol + (9Z)-octadecenoyl-CoA = 1-O-eicosanyl (9Z)-octadecenoate + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome
1,3-di-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,3-di-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-(9Z-octadecenoyl)-3-hexadecanoylglycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-3-hexadecanoylglycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 2 moreperoxisome
1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by ACAA1, MYO5B, LPGAT1, PLA2G15peroxisome
1-O-hexadecyl-3-(9Z)-octadecenoylglycerolReach from here →
1. acetyl-CoA C-acyltransferase (3-oxoeicosanoyl-CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-O-hexadecylglycerol + (9Z)-octadecenoyl-CoA = 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol + CoA
Catalysed by ACAA1, MYO5B, SCD, SCD5 and 1 moreperoxisome