CHEBI:16132

Three steps

• (2R)-3-phosphoglycerateReach from here →
  1. deoxyribose-phosphate aldolase
  2. D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)
  3. ATP:3-phospho-D-glycerate 1-phosphotransferase

  Catalysed by DERA, GAPDHS, GAPDH, PGK1 and 2 morecytosolOne of 9 routes

• 1-hexadecanoylglycerone 3-phosphateReach from here →
  1. deoxyribose-phosphate aldolase
  2. D-glyceraldehyde-3-phosphate aldose-ketose-isomerase
  3. glyceronephosphate O-acyltransferase (DHAP)

  Catalysed by DERA, TPI1, GNPATcytosol, peroxisome

• alpha-D-glucose 1,6-bisphosphateReach from here →
  1. deoxyribose-phosphate aldolase
  2. D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)
  3. 3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase

  Catalysed by DERA, GAPDHS, GAPDH, PGM2L1cytosolOne of 3 routes

• N(8)-acetylspermidineReach from here →
  1. deoxyribose-phosphate aldolase
  2. Acetaldehyde:NAD+ oxidoreductase
  3. N(8)-acetylspermidine + H2O = spermidine + acetate

  Catalysed by DERA, ALDH3A1, ALDH3B1, ALDH1A3 and 2 morecytosol

• an N-acetyl-L-cysteine-S-conjugateReach from here →
  1. deoxyribose-phosphate aldolase
  2. Acetaldehyde:NAD+ oxidoreductase
  3. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate

  Catalysed by DERA, ALDH3A1, ALDH3B1, ALDH1A3 and 2 morecytosol

• D-glyceraldehyde 3-phosphateReach from here →
  1. deoxyribose-phosphate aldolase
  2. 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
  3. 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde

  Catalysed by DERAcytosolOne of 3 routes

• alpha-D-ribose 1,5-bisphosphateReach from here →
  1. deoxyribose-phosphate aldolase
  2. D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)
  3. (2R)-3-phospho-glyceroyl phosphate + alpha-D-ribose 1-phosphate = alpha-D-ribose 1,5-bisphosphate + (2R)-3-phosphoglycerate + H(+)

  Catalysed by DERA, GAPDHS, GAPDH, PGM2L1cytosol

• D-ribulose 1-phosphateReach from here →
  1. deoxyribose-phosphate aldolase
  2. D-glyceraldehyde-3-phosphate aldose-ketose-isomerase
  3. L-xylulose 1-phosphate glycolaldehyde-lyase (glycerone-phosphate-forming)

  Catalysed by DERA, TPI1, ALDOA, ALDOB and 1 morecytosol