N-acetylcadaverine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

128 compounds within 3 steps: 2 in 1, 21 in 2, 105 in 3

Three steps

(4S)-4-hydroxy-2-oxoglutarateReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. transport of acetate and pyruvate (cytosol to extracellular)
3. (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
Catalysed by HDAC10, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosol
1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by HDAC10, ASAH1, PLA2G15
1-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15One of 4 routes
1-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine
Catalysed by HDAC10, ASAH1, PLA2G15One of 3 routes
1-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15One of 3 routes
4-acetamidobutanalReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-acetylputrescine + H2O = putrescine + acetate
3. N-Acetylputrescine:oxygen oxidoreductase(deaminating)(flavin-containing)
Catalysed by HDAC10, AOC2, AOC1, MAOA and 2 morecytosolOne of 2 routes
1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15One of 8 routes
2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15One of 2 routes
1-octadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15One of 5 routes
2-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-octadecanoyl-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by HDAC10, ASAH1, PLA2G15
1-hexadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15One of 9 routes
2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15One of 2 routes
1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15One of 3 routes
2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by HDAC10, ASAH1, PLA2G15
2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by HDAC10, ASAH1, PLA2G15
1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15One of 3 routes
1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15
2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by HDAC10, ASAH1, PLA2G15
2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by HDAC10, ASAH1, PLA2G15
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by HDAC10, ASAH1, PLA2G15
16alpha,17alpha-dihydroxyprogesteroneReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. cytochrome P450 (17alpha-hydroxyprogesterone)
3. 17alpha-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha,17alpha-dihydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by HDAC10, CYP17A1endoplasmic reticulum
2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-O-acyl-N-(acetyl)-sphing-4-enine
Catalysed by HDAC10, ASAH1, PLA2G15
2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine
Catalysed by HDAC10, ASAH1, PLA2G15
1-octadecanoyl-sn-glycero-3-phosphoserineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phosphoserine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by HDAC10, ASAH1, PLA2G15
1-O-acyl-N-(acetyl)-sphing-4-enineReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by HDAC10, ASAH1, PLA2G15One of 8 routes
N-(acetyl)-sphing-4-enine-1-phosphateReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + ATP = N-(acetyl)-sphing-4-enine-1-phosphate + ADP + H(+)
Catalysed by HDAC10, ASAH1, CERK
2-(1-hydroxyethyl)thiamine diphosphateReach from here →
1. N-acetylcadaverine + H2O = cadaverine + acetate
2. transport of acetate and pyruvate (cytosol to extracellular)
3. pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)
Catalysed by HDAC10, SLC16A4, SLC16A5, SLC16A3 and 5 moreextracellular space, cytosol, mitochondrial matrix