Compound
cortisol
No description recorded for this entry yet. Everything this graph holds about cortisol is below.
Structure
- Class
- Organic compound
- Formula
- C21H30O5
- Mass
- 362.466 g/mol
- Charge
- 0
- InChIKey
- JYGXADMDTFJGBT-VWUMJDOOSA-N
- SMILES
- [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@@]21C
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says cortisol moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
3 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
3 entities
3 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from cortisol: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Regulatory determinations
Published numbers and scores, transcribed from the body that issued them. A determination is not a finding and is not graded; it is the number, who set it, and the document it came from.
LiverTox likelihood score ELiverTox
LiverTox Likelihood Score E — despite extensive use, no evidence that the agent has caused liver injury. Chapter: "Corticosteroids". Source: LiverTox Master List (NBK571102).
The document·Public Domain (NLM/NIH)·Transcribed, not graded
Statements
3 statements
3 statements in 2 reference databases name cortisol — Human-GEM, Rhea. Press a relation to see only its rows; every count is the rows behind it.
- cortisol is metabolised by CYP11B1ProteinRhea RHEA:46100Inferred only
- cortisol is metabolised by CYP11B2ProteinRhea RHEA:46100Inferred only
- cortisol is metabolised by CYP17A1ProteinHuman-GEM MAR03257Inferred only
Other names
15 names
Every name this graph resolves to cortisol. Searching any of them lands here.
- Also called
- (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione(11β)-11,17,21-trihydroxypregn-4-ene-3,20-dione11beta-hydrocortisone11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione11β-hydrocortisone11β,17α,21-trihydroxy-4-pregnene-3,20-dione17-hydroxycorticosterone4-pregnen-11beta,17alpha,21-triol-3,20-dione4-pregnen-11β,17α,21-triol-3,20-dionehydrocortisoneKendall's compound FReichstein's substance MST 21:3;O5
- Systematic name
- 11beta,17,21-trihydroxypregn-4-ene-3,20-dione11β,17,21-trihydroxypregn-4-ene-3,20-dione