Compound

lithocholoyl-CoA

An acyl-CoA(4−) that is the tetraanion of lithocholyl-CoA, arising from deprotonation of phosphate and diphosphate functions; major species at pH 7.3.

Definition from ChEBI (CHEBI:87438), read 2026-09-23. CC BY 4.0.

CHEBI:87438ChEBI

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Structure

2D depiction

Class: Organic compound, anion
Formula: C45H70N7O18P3S
Mass: 1122.075 g/mol
Charge: -4
InChIKey: MHVCMYOMCROIEL-FYYKUXHTSA-J
SMILES: [H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@]([H])([C@]([H])(C)CCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]5O[C@@H](n6cnc7c(N)ncnc76)[C@H](O)[C@@H]5OP(=O)([O-])[O-])[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What the reference databases state

Statements

1 statement

1 statement · 1 reference database · Subject: lithocholoyl-CoA · Sources: Rhea

Order

lithocholate is converted to lithocholoyl-CoACompoundRhea RHEA:47136Inferred only

Reactions

7 reactions

lithocholate+ATP(4-)+coenzyme A(4-)lithocholoyl-CoA+AMP+diphosphate(3-)
Catalysed by SLC27A5
Reaction pageLeft to rightBalanced
Rhea RHEA:47136CC BY 4.0Reference data
lithocholoyl-CoA+cholatecholoyl-CoA+lithocholate
Reaction pageDirection not assertedBalanced
Rhea RHEA:49432CC BY 4.0Reference data
lithocholoyl-CoA+NAD(1-)CHEBI:136703+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:52596CC BY 4.0Reference data
CHEBI:137661+lithocholoyl-CoACHEBI:137663+lithocholate
Reaction pageDirection not assertedBalanced
Rhea RHEA:53764CC BY 4.0Reference data
lithocholoyl-CoA+chenodeoxycholatechenodeoxycholoyl-CoA+lithocholate
Reaction pageDirection not assertedBalanced
Rhea RHEA:53772CC BY 4.0Reference data
CHEBI:134119+lithocholoyl-CoACHEBI:137668+lithocholate
Reaction pageDirection not assertedBalanced
Rhea RHEA:53780CC BY 4.0Reference data
ursodeoxycholate+lithocholoyl-CoACHEBI:137679+lithocholate
Reaction pageDirection not assertedBalanced
Rhea RHEA:53800CC BY 4.0Reference data

Other names

7 names

Resolves to: lithocholoyl-CoA

Also called: lithocholoyl-CoA(4-)lithocholoyl-CoA(4−)lithocholoyl-coenzyme A(4-)lithocholoyl-coenzyme A(4−)lithocholyl-CoAlithocholyl-coenzyme A(4-)lithocholyl-coenzyme A(4−)