Compound
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine
A phosphatidylethanolamine 34:2 zwitterion obtained by transfer of a proton from the phosphate to the amino group of 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine.
Definition from ChEBI (CHEBI:73008), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound
- Formula
- C39H74NO8P
- Mass
- 715.994 g/mol
- Charge
- 0
- InChIKey
- HBZNVZIRJWODIB-NHCUFCNUSA-N
- SMILES
- [H][C@@](COC(=O)CCCCCCCCCCCCCCC)(COP(=O)([O-])OCC[NH3+])OC(=O)CCCCCCC/C=CC/C=CCCCCC
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
15 entities
15 entities reached.
0 reported hops15 assembled from the scaffold
- PLA2G2AProteinUNIPROT:P14555substrate ofInferred only37 paths37 endpoints
- PLAAT4ProteinUNIPROT:Q9UL19substrate ofInferred only26 paths13 endpoints
- PLA2G1BProteinUNIPROT:P04054substrate ofInferred only22 paths22 endpoints
- PLAAT3ProteinUNIPROT:P53816substrate ofInferred only22 paths11 endpoints
- PLA2G4BProteinUNIPROT:P0C869substrate ofInferred only20 paths20 endpoints
- PLA2G5ProteinUNIPROT:P39877substrate ofInferred only17 paths17 endpoints
- PLA2G10ProteinUNIPROT:O15496substrate ofInferred only14 paths14 endpoints
- PLA2G4DProteinUNIPROT:Q86XP0substrate ofInferred only14 paths14 endpoints
- PLA2G4FProteinUNIPROT:Q68DD2substrate ofInferred only13 paths13 endpoints
- PLA2G2DProteinUNIPROT:Q9UNK4substrate ofInferred only12 paths12 endpoints
- PLA2G2FProteinUNIPROT:Q9BZM2substrate ofInferred only11 paths11 endpoints
- PLA2G2EProteinUNIPROT:Q9NZK7substrate ofInferred only11 paths11 endpoints
What the reference databases state
Statements
19 statements
19 statements · 1 reference database · Subject: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine · Sources: Rhea
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G10ProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G15ProteinRhea RHEA:38831Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G15ProteinRhea RHEA:38835Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G1BProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G2AProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G2DProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G2EProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G2FProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G3ProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G4BProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G4DProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G4FProteinRhea RHEA:40815Inferred only
Show the remaining 7
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G5ProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT2ProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT2ProteinRhea RHEA:45164Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT3ProteinRhea RHEA:40815Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT3ProteinRhea RHEA:45164Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT4ProteinRhea RHEA:45164Inferred only
- 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT4ProteinRhea RHEA:40815Inferred only
Reactions
7 reactions
1-hexadecanoyl-sn-glycero-3-phosphoethanolamine+(9Z,12Z)-octadecadienoyl-CoA1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine+coenzyme A(4-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:36019CC BY 4.0Reference data
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine+N-(acetyl)-sphing-4-enine2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine+1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by PLA2G15
Reaction pageLeft to rightBalanced
Rhea RHEA:38831CC BY 4.0Reference data
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine+N-(acetyl)-sphing-4-enine1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine+1-hexadecanoyl-sn-glycero-3-phosphoethanolamine
Catalysed by PLA2G15
Reaction pageLeft to rightBalanced
Rhea RHEA:38835CC BY 4.0Reference data
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine+water1-hexadecanoyl-sn-glycero-3-phosphoethanolamine+(9Z,12Z)-octadecadienoate+hydron
Catalysed by PLA2G10 or PLA2G1B or PLA2G4B or PLA2G2A or PLA2G5 or PLAAT3 or PLA2G4F or PLA2G4D or PLA2G2F or PLAAT2 or PLA2G3 or PLA2G2E and 2 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:40815CC BY 4.0Reference data
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine+1-hexadecanoyl-sn-glycero-3-phosphocholine1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+1-hexadecanoyl-sn-glycero-3-phosphoethanolamine
Reaction pageDirection not assertedBalanced
Rhea RHEA:43820CC BY 4.0Reference data
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine+water2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine+hexadecanoate+hydron
Catalysed by PLAAT3 or PLAAT2 or PLAAT4
Reaction pageLeft to rightBalanced
Rhea RHEA:45164CC BY 4.0Reference data
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine+1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol+1-hexadecanoyl-sn-glycero-3-phosphoethanolamine
Reaction pageDirection not assertedBalanced
Rhea RHEA:65040CC BY 4.0Reference data
Other names
11 names
Resolves to: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine
- Also called
- 1-C16:0-2-C18:2(omega-6)-phosphatidylethanolamine zwitterion1-C16:0-2-C18:2(ω-6)-phosphatidylethanolamine zwitterion1-hexadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine zwitterion1-hexadecanoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine zwitterion1-palmitoyl-2-linoleoyl-GPE1-palmitoyl-2-linoleoyl-GPE (16:0/18:2)1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine zwitterionGPE(16:0/18:2(9Z,12Z))GPE(16:0/18:2)PE(16:0/18:2(9Z,12Z))
- Systematic name
- 2-azaniumylethyl (2R)-3-(hexadecanoyloxy)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl phosphate