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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed

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Atlas Graph Access Compounds Outcomes Proteins Interactions Papers Articles Pathways Processes Anatomy Cell types Organisms Materials Assessments

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Catalyst

The evidence graph for human biochemistry. Every edge carries its source, its study design, and a grade computed from both.

The graph

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Proteins
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Reference layer

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Processes
Anatomy
Cell types
Organisms
Materials
Assessments

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Reaction

17beta-estradiol+NADP(3-)estrone+NADPH(4-)+hydron

Right to left · Balance undeterminable

Inferred

Reference data, not a finding. Evidence key

Catalysts

AKR1B15
HSD17B6
HSD17B1
AKR1C4
HSD17B3
AKR1C3
AKR1C2
HSD17B7
AKR1C1
HSD17B12
DHRS11
HSD17B11

Rhea RHEA:24616·2026-08-19·CC BY 4.0Reference data