Proteins/UNIPROT:O95153

TSPOAP1

ProteinUNIPROT:O95153

Required for synaptic transmission regulation. It probably controls the recruitment of voltage-gated calcium channels to the presynaptic membrane, and modulates neurotransmitter release..

Function from UniProtKB (O95153), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

dystonia 22, juvenile-onset has a germline basis in TSPOAP1DiseaseGenCC HGNC:16831|MONDO:0957539Inferred only
TH-deficient dopa-responsive dystonia has a germline basis in TSPOAP1DiseaseGenCC HGNC:16831|MONDO:0011551Inferred only

Statements

20 statements

20 statements · 3 reference databases · Subject: TSPOAP1 · Sources: gene ontology, Hetionet, Reactome

Order

TSPOAP1 covaries with AMBRA1ProteinHetionet hetionet:covaries:55626-9256Inferred only
TSPOAP1 covaries with ARAP1ProteinHetionet hetionet:covaries:116985-9256Inferred only
TSPOAP1 covaries with EDC4ProteinHetionet hetionet:covaries:23644-9256Inferred only
TSPOAP1 covaries with KLC2ProteinHetionet hetionet:covaries:64837-9256Inferred only
SREBF2 covaries with TSPOAP1ProteinHetionet hetionet:covaries:6721-9256Inferred only
TNRC6B covaries with TSPOAP1ProteinHetionet hetionet:covaries:23112-9256Inferred only
TSPOAP1 participates in Acetylcholine Neurotransmitter Release CyclePathwayReactome R-HSA-264642Inferred only
TSPOAP1 participates in Dopamine Neurotransmitter Release CyclePathwayReactome R-HSA-212676Inferred only
TSPOAP1 participates in Glutamate Neurotransmitter Release CyclePathwayReactome R-HSA-210500Inferred only
TSPOAP1 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
TSPOAP1 participates in Metabolism of lipidsPathwayReactome R-HSA-556833Inferred only
TSPOAP1 participates in Metabolism of steroid hormonesPathwayReactome R-HSA-196071Inferred only

Show the remaining 8

TSPOAP1 participates in Metabolism of steroidsPathwayReactome R-HSA-8957322Inferred only
TSPOAP1 participates in Neuronal SystemPathwayReactome R-HSA-112316Inferred only
TSPOAP1 participates in Neurotransmitter release cyclePathwayReactome R-HSA-112310Inferred only
TSPOAP1 participates in Norepinephrine Neurotransmitter Release CyclePathwayReactome R-HSA-181430Inferred only
TSPOAP1 participates in Pregnenolone biosynthesisPathwayReactome R-HSA-196108Inferred only
TSPOAP1 participates in Serotonin Neurotransmitter Release CyclePathwayReactome R-HSA-181429Inferred only
TSPOAP1 participates in Transmission across Chemical SynapsesPathwayReactome R-HSA-112315Inferred only
TSPOAP1 regulates regulation of neurotransmitter secretionBiological processgene ontology O95153|GO:0046928Inferred only

Other names

10 names

Resolves to: TSPOAP1

Also called: BZRAP1KIAA0612PBR-IPPeripheral benzodiazepine receptor-interacting proteinPRAX-1RBP1RIM-BP1RIMBP1RIMS-binding protein 1TSPO-associated protein 1

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