Pathway
Chronic hyperglycemia impairment of neuron function
Chronic excess of glucose (chronic hyperglycemia) impairs neuron function via the polyol pathway, causing ROS and RNS eventually. These activate nuclear transcription factors that increase the expr...
WP:5283
What the reference databases state
Statements
45 statements
45 statements · 1 reference database · Subject: Chronic hyperglycemia impairment of neuron function · Sources: WikiPathways
- AGER participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- BDNF participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- C3 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP1 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP10 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP11 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP12 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP13 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP14 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP15 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP16 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP17 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
Show the remaining 33
- MMP19 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP2 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP20 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP21 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP23B participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP24 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP25 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP28 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP3 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP7 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP8 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- MMP9 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- NOS2 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- PRKCA participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- PRKCB participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- PRKCD participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- PRKCE participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- PRKCG participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- PRKCH participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- PRKCI participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- PRKCQ participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- PRKCZ participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- PRKD3 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- SCN10A participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- SCN8A participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- SCN9A participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- SLC2A1 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- SLC2A3 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- SNAP25 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- SORD participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- TKTL1 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- TRPA1 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only
- TRPV1 participates in Chronic hyperglycemia impairment of neuron functionProteinWikiPathways WP5283Inferred only