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Proteins/UNIPROT:Q9NQR4
Has omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively..
Function from UniProtKB (Q9NQR4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
55 statements
55 statements · 5 reference databases · Subject: NIT2 · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea
5 reactions
2-oxoglutaramate+water2-oxoglutarate(2-)+proton+ammonium
Catalysed by NIT2
Reaction pageLeft to rightBalancedEC 3.5.1.3cytosol
Human-GEM MAR04114CC BY 4.0Reference data
2-oxoglutaramate+water2-oxoglutarate(2-)+proton+ammonium
Catalysed by NIT2
1 name
Resolves to: NIT2
Human-GEM MAR04115CC BY 4.0Reference data
a monoamide of a dicarboxylate+watera dicarboxylate+ammonium
Catalysed by NIT2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:11716CC BY 4.0Reference data
2-oxoglutaramate+water2-oxoglutarate(2-)+ammonium
Catalysed by NIT2
Reaction pageLeft to rightBalanced
Rhea RHEA:32963CC BY 4.0Reference data
2-oxosuccinamate+wateroxaloacetate+ammonium
Catalysed by NIT2
Reaction pageLeft to rightBalanced
Rhea RHEA:59412CC BY 4.0Reference data