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Proteins/UNIPROT:Q13261
High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation. In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner. Expression of different isoforms may alter or interfere with signal transduction..
[Isoform 5]: Does not bind IL15..
[Isoform 6]: Does not bind IL15..
[Isoform 7]: Does not bind IL15..
[Isoform 8]: Does not bind IL15..
Function from UniProtKB (Q13261), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
79 statements
79 statements · 4 reference databases · Subject: IL15RA · Sources: gene ontology, Hetionet, Reactome, WikiPathways
8 names
Resolves to: IL15RA