Proteins/UNIPROT:Q5VV67

PPRC1

ProteinUNIPROT:Q5VV67

Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes..

Function from UniProtKB (Q5VV67), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

30 statements

30 statements · 4 reference databases · Subject: PPRC1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

MDC1 covaries with PPRC1ProteinHetionet hetionet:covaries:23082-9656Inferred only
ELOC interacts with PPRC1ProteinHetionet hetionet:interacts:23082-6921Inferred only
NRF1 interacts with PPRC1ProteinHetionet hetionet:interacts:23082-4899Inferred only
UBC interacts with PPRC1ProteinHetionet hetionet:interacts:23082-7316Inferred only
USF1 interacts with PPRC1ProteinHetionet hetionet:interacts:23082-7391Inferred only
USF2 interacts with PPRC1ProteinHetionet hetionet:interacts:23082-7392Inferred only
PPRC1 participates in Energy metabolismPathwayWikiPathways WP1541Inferred only
PPRC1 participates in Mitochondrial biogenesisPathwayReactome R-HSA-1592230Inferred only
PPRC1 participates in Mitochondrial gene expressionPathwayWikiPathways WP391Inferred only
PPRC1 participates in Organelle biogenesis and maintenancePathwayReactome R-HSA-1852241Inferred only
PPRC1 participates in Transcriptional activation of mitochondrial biogenesisPathwayReactome R-HSA-2151201Inferred only
PPRC1 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q5VV67|GO:0045944Inferred only

Show the remaining 18

AXL increases the expression of PPRC1ProteinHetionet hetionet:regulates:558-23082Inferred only
CCT7 increases the expression of PPRC1ProteinHetionet hetionet:regulates:10574-23082Inferred only
CDKN1A increases the expression of PPRC1ProteinHetionet hetionet:regulates:1026-23082Inferred only
COPB2 increases the expression of PPRC1ProteinHetionet hetionet:regulates:9276-23082Inferred only
GNB1 decreases the expression of PPRC1ProteinHetionet hetionet:regulates:2782-23082Inferred only
GPR146 increases the expression of PPRC1ProteinHetionet hetionet:regulates:115330-23082Inferred only
HOMER2 decreases the expression of PPRC1ProteinHetionet hetionet:regulates:9455-23082Inferred only
IL15RA decreases the expression of PPRC1ProteinHetionet hetionet:regulates:3601-23082Inferred only
KRT19 increases the expression of PPRC1ProteinHetionet hetionet:regulates:3880-23082Inferred only
NOLC1 decreases the expression of PPRC1ProteinHetionet hetionet:regulates:9221-23082Inferred only
SC5D decreases the expression of PPRC1ProteinHetionet hetionet:regulates:6309-23082Inferred only
SLC35B1 increases the expression of PPRC1ProteinHetionet hetionet:regulates:10237-23082Inferred only
SNW1 increases the expression of PPRC1ProteinHetionet hetionet:regulates:22938-23082Inferred only
TP53BP2 decreases the expression of PPRC1ProteinHetionet hetionet:regulates:7159-23082Inferred only
TRIP13 increases the expression of PPRC1ProteinHetionet hetionet:regulates:9319-23082Inferred only
ZFX increases the expression of PPRC1ProteinHetionet hetionet:regulates:7543-23082Inferred only
ZMIZ1 decreases the expression of PPRC1ProteinHetionet hetionet:regulates:57178-23082Inferred only
ZNF589 increases the expression of PPRC1ProteinHetionet hetionet:regulates:51385-23082Inferred only

Other names

3 names

Resolves to: PPRC1

Also called: KIAA0595PGC-1-related coactivatorPRC

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